16/08/2026
Does one side of your face always feel more sensitive during injections?
You’re not imagining the pain, but it may not be because your left or right side is “weaker.”
There’s an older pain theory suggesting the left side of the body might hurt more because of how the right brain processes emotion. It sounds plausible, but when researchers looked at facial pain specifically, they didn’t find a significant left-versus-right difference.
What often matters more is order!
The second side can feel sharper because your brain has already experienced the first pinch and starts anticipating the next one. This is called nocebo hyperalgesia: expectation can amplify pain through real, measurable neural pathways.
So no, it’s not “all in your head” in the dismissive sense. Your brain and nervous system can change how strongly pain signals feel.