20/06/2026
Current evidence does not show a negative long-term effect of GLP-1 agonists on male fertility, and some data suggest the drugs may offer benefits, the results of a systematic review found.
“One thing we proved is that they do not harm the reproductive axis in men. There was no inhibitory effect, so we can counsel our patients that the drugs don’t impact the reproductive system negatively,” study author Pratibha Natesh, MBBS, Warwick Medical School, Coventry, England, told Medscape Medical News.
Still, the data in this area are sparse, she noted. “We only found three randomized controlled trials that evaluated the impact of the GLP-1 analog on the reproductive system with prolonged use. … But the results were quite encouraging.” https://mdsc.pe/4anP7Cn