29/07/2026
Pearl For MRCP Part-2
Mnemonic: "A.B.C.D.S."
Antiplatelets
Beta-blockers
Cholesterol control (statins)
Diet and lifestyle changes
Stabilize with ACE inhibitors.
★ MI Complications
Common Complications:
VSD: Pansystolic murmur
Mitral Regurgitation: Rupture of papillary muscles
Tamponade: Free wall rupture
Heart Failure or Cardiogenic Shock
Most Confirmatory Investigation: Echocardiography
Most Appropriate Next Step: Stabilize hemodynamics
Most Appropriate Intervention: Urgent surgical repair for mechanical complications
Mnemonic: "C.R.A.S.H."
CHF or cardiogenic shock
Rupture (VSD, free wall)
Arrhythmias
Stabilize with supportive care
Hemodynamic collapse = surgery.
★ Marfan Syndrome and Aortic Dissection
Marfan Syndrome:
Scenario: Tall stature, arachnodactyly, and lens dislocation + On exam: high-arched palate, pectus deformity + Investigation shows: aortic root dilation on echocardiography >>
Most Likely Dx: Marfan Syndrome
Most Common Cause: FBN1 gene mutation
Most Confirmatory Investigation: Genetic testing
Most Appropriate Next Step: Echocardiography screening for aortic complications
Most Appropriate Intervention: Beta-blockers or losartan; prophylactic aortic surgery
Aortic Dissection:
Scenario: Tearing chest pain radiating to the back + On exam: unequal BP in limbs + Investigation shows: widened mediastinum on CXR >>
Most Likely Dx: Aortic Dissection
Most Common Causes: Hypertension, connective tissue disorders
Most Confirmatory Investigation: CT angiography
Most Appropriate Next Step: Control BP with IV beta-blockers
Most Appropriate Intervention: Type A → urgent surgery; Type B → medical management