Pathology cases and tips

Pathology cases and tips This page was created to display rare and fine pathology cases as well as tips

🔬 Pathology QuizClinical history:70-year-old male patient with cervical lymphadenopathy.H&E and IHC findings are shown b...
18/07/2026

🔬 Pathology Quiz

Clinical history:
70-year-old male patient with cervical lymphadenopathy.

H&E and IHC findings are shown below.

Questions:
1️⃣ What is the diagnosis?
2️⃣ What are the IHC markers shown?

For beginnersMore microscopic pictures below
11/07/2026

For beginners
More microscopic pictures below

02/07/2026
02/07/2026
High-Grade CD20-Positive Lymphoid Neoplasm with Very High Ki-67: What Should Be in Your IHC Panel?A monomorphic high-gra...
26/06/2026

High-Grade CD20-Positive Lymphoid Neoplasm with Very High Ki-67: What Should Be in Your IHC Panel?

A monomorphic high-grade CD20-positive lymphoid proliferation with a very high Ki-67 index requires a differential-directed IHC panel.

An initial panel may include Cyclin D1 and CD5 for blastoid mantle cell lymphoma; TdT ± CD34 for B-lymphoblastic lymphoma; CD10, BCL6 and MYC for Burkitt/high-grade B-cell lymphoma; and MUM1, CD138 ± light chains/EBER for plasmablastic or plasma-cell differentiation.

Final interpretation must integrate morphology, clinical findings and the complete immunophenotype.

22/06/2026

Answer in 1st comment

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