06/03/2026
🧬What are Polynucleotides 🧬
Polynucleotides are chains of DNA fragments (often derived from purified salmon or trout DNA) used in regenerative aesthetic treatments. They work by stimulating skin repair rather than filling volume.
A well-known example is Plinest or Ameela , which are commonly used for delicate areas like the eyes.
🧬What They Do Around the Eyes👁️
🧬When injected into the under-eye (tear trough) or crow’s feet area, they can:
• Stimulate fibroblasts → more collagen and elastin
• Improve skin thickness
• Increase hydration
• Reduce fine lines and crepey texture
• Help improve dark circles caused by thin skin
Unlike dermal fillers, they don’t add volume. Instead they repair and regenerate the skin.
🧬What are the Treatments like 🧬
• Tiny injections around the under-eye area
• Takes about 20–30 minutes
• Usually 2–3 sessions spaced 2–4 weeks apart
• Results gradually appear over 4–8 weeks
🧬Recovery🧬
Typical side effects are mild:
• Small bumps for 24–48 hours
• Slight swelling or bruising
• Minimal downtime
Because the eye area is delicate, it’s important the treatment is done by an experienced aesthetic doctor.
Who It’s Best For🙋♂️😍🙋♀️
Polynucleotides work well for:
• Early aging around the eyes
• Thin, crepey under-eye skin
• Dark circles from skin transparency
• People who don’t want filler
They are not ideal for large tear trough hollows where volume replacement might be needed.
⸻
🧬Polynucleotides VS Tear Trough filler 💉
Improves skin quality Adds volume
Gradual results Immediate results
Very natural Can look puffy if overdone
Usually 1 session Usually 1 session
For more information book in for a consultation
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