16/09/2026
Cancer, diabetes, depression and accelerated ageing share a common thread most training treats separately.
Mitochondrial Dysfunction and Chronic Disease: The Influence of Nutrition and Lifestyle examines mitochondria as central regulators of cellular metabolism and signalling, influencing biosynthetic pathways, immune responses, cell proliferation and programmed cell death, with dysfunction implicated in metabolic syndrome and diabetes, cardiovascular disease, neurodegenerative and mood disorders, cancer, and accelerated ageing.
The session covers how oxidative stress, environmental toxicants and pharmaceuticals, caloric excess, glucotoxicity and lipotoxicity impair mitochondrial function, with particular focus on mitohormesis, where controlled, transient mitochondrial stress activates adaptive responses that enhance cellular resilience.
By the end, you'll be able to review the cellular biology of mitochondria and their role in energy production and metabolic signalling, discuss how oxidative stress and environmental and dietary factors contribute to mitochondrial dysfunction, chronic disease and ageing, and examine how physical activity, dietary strategies and selected supplements may promote beneficial mitochondrial adaptation through mitohormesis, biogenesis and quality control.
Bob has practised family medicine in Boulder, Colorado, since 1983, and has served as Medical Director of Boulder Wellcare since 2002. He's an original, long-standing member of the core faculty for the Institute for Functional Medicine in Federal Way, and received the Linus Pauling Functional Medicine Award from IFM in 2015 for his years of mentoring and training healthcare providers.
FMC 2026 takes place on the 14th and 15th of November at the Hogan Suite, Croke Park, Dublin. Comment FMC or click the link in bio to join us for the full session in Croke Park in November.