13/06/2026
Can a cheap mineral capsule really move insomnia? The largest RCT to date says: a little -- and most in people who need it.
Schuster et al. (Nature and Science of Sleep, 2025) ran a double-blind, placebo-controlled trial: 155 adults with poor sleep got 250 mg of elemental magnesium as bisglycinate or placebo, nightly for four weeks.
The magnesium group cut Insomnia Severity Index scores more than placebo (-3.9 vs -2.3, p=0.049). The biggest gains were in people who started low in dietary magnesium.
Caveats: effect size was small (Cohen's d = 0.2), the 1.6-point ISI gap sits below the usual 6-point clinical-meaningfulness threshold, and sleep was self-reported. Real but modest.
Today's drop: if sleep is uneven and your diet is low in magnesium-rich foods (greens, legumes, nuts, seeds), try 200-250 mg of elemental magnesium as glycinate, 30-60 minutes before bed, for four weeks.
Sleep is one of the most underrated metabolic levers in longevity -- poor sleep drives insulin resistance, cortisol, and visceral fat.
Full breakdown coming on the Health Longevity Secrets podcast https://www.youtube.com/
Source: https://pubmed.ncbi.nlm.nih.gov/40918053/