Med Dose

Med Dose Pharmacist assistant

12/04/2026

ئێکەم خەلەکە : ئیبوپروفین، بۆ پتر زانیاریا لسەر ڤی دەرمانی👇🏻
Ibuprofen: what you must know before using it ⚠️

💊 Class: NSAID (Propionic acid derivative)
🔬 Mechanism: Inhibits COX-1 & COX-2 → ↓ prostaglandins → ↓ pain, inflammation, fever



🧠 Uses:
• Headache
• Muscle pain
• Fever
• Toothache
• Inflammatory conditions



⏱ Pharmacokinetics:
• Onset: 30–60 minutes
• Duration: 4–6 hours



💉 Routes of administration:
• Oral (tablets, syrup)
• Topical (gel/cream)
• IV (in hospital settings)



💊 Dosage (Adults):
• Usual: 200–400 mg every 6–8 hours
• Max OTC: 1200 mg/day
• Max prescription: up to 2400–3200 mg/day (under medical supervision)



🚨 Side Effects:

❗ Gastritis, stomach pain
❗ Peptic ulcer, GI bleeding
❗ Nausea, vomiting
❗ Kidney impairment
❗ Increased blood pressure
❗ Rare: allergic reactions (rash, bronchospasm)



⚠️ Precautions:
• Take after food
• Avoid in peptic ulcer patients
• Caution in elderly
• Use carefully in kidney disease & hypertension
• Avoid long-term use without medical advice



🔄 Drug Interactions:

⚠️ Increased kidney risk with:
• Diuretics (e.g. Furosemide)
• ACE inhibitors

⚠️ Increased bleeding risk with:
• Anticoagulants
• Other NSAIDs



🚫 Avoid / Contraindications:
• Active GI bleeding or ulcer
• Severe kidney disease
• NSAID allergy
• Late pregnancy



💡 Pro Tip:

Use the lowest effective dose for the shortest time

12/04/2026

NSAIDs drugs

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Zakho

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