12/04/2026
ئێکەم خەلەکە : ئیبوپروفین، بۆ پتر زانیاریا لسەر ڤی دەرمانی👇🏻
Ibuprofen: what you must know before using it ⚠️
💊 Class: NSAID (Propionic acid derivative)
🔬 Mechanism: Inhibits COX-1 & COX-2 → ↓ prostaglandins → ↓ pain, inflammation, fever
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🧠 Uses:
• Headache
• Muscle pain
• Fever
• Toothache
• Inflammatory conditions
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⏱ Pharmacokinetics:
• Onset: 30–60 minutes
• Duration: 4–6 hours
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💉 Routes of administration:
• Oral (tablets, syrup)
• Topical (gel/cream)
• IV (in hospital settings)
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💊 Dosage (Adults):
• Usual: 200–400 mg every 6–8 hours
• Max OTC: 1200 mg/day
• Max prescription: up to 2400–3200 mg/day (under medical supervision)
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🚨 Side Effects:
❗ Gastritis, stomach pain
❗ Peptic ulcer, GI bleeding
❗ Nausea, vomiting
❗ Kidney impairment
❗ Increased blood pressure
❗ Rare: allergic reactions (rash, bronchospasm)
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⚠️ Precautions:
• Take after food
• Avoid in peptic ulcer patients
• Caution in elderly
• Use carefully in kidney disease & hypertension
• Avoid long-term use without medical advice
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🔄 Drug Interactions:
⚠️ Increased kidney risk with:
• Diuretics (e.g. Furosemide)
• ACE inhibitors
⚠️ Increased bleeding risk with:
• Anticoagulants
• Other NSAIDs
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🚫 Avoid / Contraindications:
• Active GI bleeding or ulcer
• Severe kidney disease
• NSAID allergy
• Late pregnancy
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💡 Pro Tip:
Use the lowest effective dose for the shortest time