09/06/2026
Syphilis rash is a non-itchy skin eruption that usually occurs during secondary syphilis. It can appear as reddish-brown or dark spots and bumps on the body, including the palms and soles. Because it can mimic many other skin conditions, syphilis is known as "the great imitator." Early treatment with benzathine penicillin G is highly effective. Please contact health professional.