06/09/2026
According to the latest WHO malaria guidance, artemether–lumefantrine is now the preferred treatment for uncomplicated P. falciparum malaria in all trimesters, including the first trimester. SP should not be used for preventive IPTp before 13 weeks. �
Iris +1
Updated 9:16 video content
1st trimester — 0–12 weeks
For confirmed uncomplicated malaria: Artemether–lumefantrine (AL), prescribed according to the patient's weight and clinical assessment.
For prevention: No IPTp-SP yet. Do not use sulfadoxine–pyrimethamine for IPTp in the first trimester. �
Iris
2nd trimester — 13–27 weeks
For prevention: Sulfadoxine–pyrimethamine (SP/IPTp) can begin from 13 weeks, with subsequent doses at least one month apart.
For confirmed malaria: an appropriate ACT such as artemether–lumefantrine is used according to treatment guidelines. �
World Health Organization +1
3rd trimester — 28–40 weeks
For prevention: Continue IPTp-SP at the recommended intervals through pregnancy, provided doses are appropriately spaced.
For confirmed malaria: ACT treatment such as artemether–lumefantrine is used according to clinical guidance. �
Iris +1
Important video disclaimer: “Do not buy or take antimalarial medicines on your own during pregnancy. Confirm malaria and seek advice from a qualified healthcare professional.”
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