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Lamassu BioTech Accelerating treatment, means saving more lives.

โœˆ๏ธ Meet Lamassu Biotech at ESMO - European Society for Medical Oncology Congress 2026 in Madrid, Spain๐Ÿ”ฌ Principal Invest...
10/23/2026

โœˆ๏ธ Meet Lamassu Biotech at ESMO - European Society for Medical Oncology Congress 2026 in Madrid, Spain

๐Ÿ”ฌ Principal Investigator Peter Anderson, MD, PhD, an oncologist and sarcoma specialist at Cleveland Clinic, will present positive interim findings from the ongoing Phase I/II first-in-human clinical trial of SA53, Lamassu's novel oral MDM2 inhibitor.

๐Ÿงฌ SA53 is being developed as a targeted therapeutic approach designed to restore p53 activity in tumors retaining wild-type p53. If successful, SA53 may provide new hope for up to 50% of cancer patients.

๐Ÿค Connect with Dr. Anderson and Lamassu Biotechโ€™s team at ESMO to learn more about our research and the ongoing trial!

10/22/2026

๐ŸงฌSA53 works by triggering the bodyโ€™s natural defense mechanism, p53, which inhibits or blocks a protein called MDM2. MDM2 is the most important factor that regulates or blocks a protein called p53. p53 works by suppressing or โ€œputting the brakes onโ€ the ability of cancers to grow, spread, and resist anti-cancer treatments. The p53 pathway is one of the most important natural defense mechanisms your body has against cancer. p53 activity is normally increased in response to many pro-cancer conditions. However, nearly all cancers find ways to bypass or prevent the activity of p53.

๐Ÿฉบ Lamassuโ€™s clinical trial focuses on determining a safe dosage for future trials, understanding pharmacokinetic profiles, and assessing early signs of effectiveness in treating soft tissue sarcomas and solid tumors with wild-type p53. The main goal is to advance SA53 through trials to offer a potential new and effective treatment option for patients.

๐Œ๐ƒ๐Œ๐Ÿ: ๐“๐ก๐ž ๐•๐ข๐ฅ๐ฅ๐š๐ข๐ง MDM2 gene prevents the Guardian of the Genome - p53 โ€“ from stopping damaged cells from multiplying. Wh...
10/19/2026

๐Œ๐ƒ๐Œ๐Ÿ: ๐“๐ก๐ž ๐•๐ข๐ฅ๐ฅ๐š๐ข๐ง

MDM2 gene prevents the Guardian of the Genome - p53 โ€“ from stopping damaged cells from multiplying. When too much MDM2 protein is produced, p53 is destroyed and abnormal cells โ€“ cancer cells โ€“ multiply without control. Lamassuโ€™s innovative SA53 therapy helps reactivate p53 by preventing MDM2 from โ€˜locking upโ€™ the Guardian.

The ongoing Phase 1/2 trial, conducted in collaboration with the National Institutes of Health (NIH) and Cleveland Clinic, is designed to determine the safety, tolerability, pharmacokinetics, and preliminary efficacy of SA53.

Learn more at www.lamassubiotech.com/sa53/.

10/15/2026

๐Œ๐ƒ๐Œ๐Ÿ ๐ข๐ฌ ๐ญ๐ก๐ž ๐ฆ๐จ๐ฌ๐ญ ๐ข๐ฆ๐ฉ๐จ๐ซ๐ญ๐š๐ง๐ญ ๐Ÿ๐š๐œ๐ญ๐จ๐ซ ๐ญ๐ก๐š๐ญ ๐ซ๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ž๐ฌ ๐จ๐ซ ๐›๐ฅ๐จ๐œ๐ค๐ฌ ๐š ๐ฉ๐ซ๐จ๐ญ๐ž๐ข๐ง ๐œ๐š๐ฅ๐ฅ๐ž๐ ๐ฉ๐Ÿ“๐Ÿ‘ - ๐š๐ฅ๐ฌ๐จ ๐ค๐ง๐จ๐ฐ๐ง ๐š๐ฌ ๐ญ๐ก๐ž "๐†๐ฎ๐š๐ซ๐๐ข๐š๐ง ๐จ๐Ÿ ๐ญ๐ก๐ž ๐†๐ž๐ง๐จ๐ฆ๐ž."

P53 works by suppressing the ability of cancers to grow, spread, and resist anti-cancer treatments. P53's role in preventing tumor formation by inducing programmed cell death in response to cellular stress makes it a key target for cancer therapy.

Learn more at www.LamassuBiotech.com/sa53/.

๐“๐ก๐ž ๐๐ž๐ฐ ๐‡๐ž๐ซ๐จ Lamassu Biotechโ€™s novel, genetically targeted therapeutic ๐’๐€๐Ÿ“๐Ÿ‘ (๐’elective ๐€ctivator of ๐ฉ๐Ÿ“๐Ÿ‘) works by trigge...
10/13/2026

๐“๐ก๐ž ๐๐ž๐ฐ ๐‡๐ž๐ซ๐จ

Lamassu Biotechโ€™s novel, genetically targeted therapeutic ๐’๐€๐Ÿ“๐Ÿ‘ (๐’elective ๐€ctivator of ๐ฉ๐Ÿ“๐Ÿ‘) works by triggering the bodyโ€™s natural defense mechanism, p53 โ€“ the Guardian of the Genome - to block or inhibit a protein called MDM2.

๐’๐€๐Ÿ“๐Ÿ‘ is a designed to reactivate the tumor suppressor protein p53 to induce highly targeted tumor cell death and inhibit growth without the systemic toxicity often associated with traditional chemotherapy. ๐’๐€๐Ÿ“๐Ÿ‘ is being investigated in adult patients with sarcoma and other solid tumors who possess the p53 wild-type gene and who currently have limited therapeutic options.

Visit lamassubiotech.com/sa53/ to learn more about how Lamassu Biotechโ€™s novel genetically targeted therapy could transform the way we treat cancer.

10/08/2026

๐€ ๐ง๐ž๐ฐ ๐œ๐š๐ง๐œ๐ž๐ซ ๐Ÿ๐ข๐ ๐ก๐ญ๐ข๐ง๐  ๐ญ๐ž๐š๐ฆ ๐ญ๐ก๐š๐ญ ๐œ๐จ๐ฎ๐ฅ๐ ๐ญ๐ซ๐š๐ง๐ฌ๐Ÿ๐จ๐ซ๐ฆ ๐ญ๐ก๐ž ๐ฐ๐š๐ฒ ๐ฐ๐ž ๐ญ๐ซ๐ž๐š๐ญ ๐ญ๐ก๐ž ๐๐ข๐ฌ๐ž๐š๐ฌ๐ž.

Developed by Lamassu Biotech, ๐’๐€๐Ÿ“๐Ÿ‘ (๐’elective ๐€ctivator of ๐ฉ๐Ÿ“๐Ÿ‘) is a novel therapeutic, currently in human trials, that targets p53 wild-type sarcomas, malignant tumors of connective or non-epithelial tissue. SA53 works by triggering the bodyโ€™s natural defense mechanism, p53, which inhibits or blocks a protein called MDM2. MDM2 is the most important factor that regulates or blocks a protein called p53. p53 works by suppressing or โ€œputting the brakes onโ€ the ability of cancers to grow, spread, and resist anti-cancer treatments. The p53 pathway is one of the most important natural defense mechanisms your body has against cancer.

Learn more at www.LamassuBiotech.com/sa53/.

๐“๐ก๐ž ๐†๐ฎ๐š๐ซ๐๐ข๐š๐ง Often called the โ€œGuardian of the Genome,โ€ p53 is a crucial tumor suppressor gene that prevents tumor forma...
10/06/2026

๐“๐ก๐ž ๐†๐ฎ๐š๐ซ๐๐ข๐š๐ง

Often called the โ€œGuardian of the Genome,โ€ p53 is a crucial tumor suppressor gene that prevents tumor formation by inducing programmed cell death. When the DNA in a cell becomes damaged p53 plays a critical role in determining whether the cancerous cell survives. If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, The Guardian prevents the cell from dividing and signals it to undergo apoptosis. By stopping cells with mutated or damaged DNA from dividing, p53 helps prevent the development of tumors.

Visit www.lamassubiotech.com/sa53/ to learn more about how Lamassu Biotechโ€™s novel genetically targeted SA53 therapy that works with p53 to fight up to 50 percent of all cancers.

Lamassu Biotech's team is on the road this week. Head of Business Development Olivier Jarry will be attending Sach Assoc...
10/05/2026

Lamassu Biotech's team is on the road this week. Head of Business Development Olivier Jarry will be attending Sach Associates' first annual European Healthcare Impact Summit and the 26th annual Biotech in Europe Forum.

October is Breast Cancer Awareness Month, a time to raise awareness, show support, and take action in the fight against ...
10/01/2026

October is Breast Cancer Awareness Month, a time to raise awareness, show support, and take action in the fight against breast cancer. Whether you're a survivor or someone battling breast cancer diagnosis, our team at Lamassu Biotech honors and supports you.

Nearly 2 million Americans receive a cancer diagnosis each year. But government agencies and researchers have traditiona...
09/30/2026

Nearly 2 million Americans receive a cancer diagnosis each year. But government agencies and researchers have traditionallyโ€”and understandablyโ€”focused on more common cancers that affect the largest numbers of patients. This can leave people battling a rare cancer diagnoses with few treatment options. At Lamassu Biotech our novel genetically targeted therapy SA53, works by triggering the bodyโ€™s natural defense mechanism, p53, which inhibits or blocks a protein called MDM2. The p53 pathway is one of the most important natural defense mechanisms your body has against cancer. Learn more at LamassuBiotech.com/sa53/.

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