Dr. Casey Peavler

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Dr. Casey Peavler 🩺 Board-certified Internal Medicine M.D.
🌱 Functional Medicine | Metabolic & Mitochondrial Oncology Education Casey Peavler is a Medical Doctor (M.D.)
(2)

who is Board Certified in Internal Medicine. Dr. Peavler has specialized training in integrative, functional, and mitochondrial medicine. He practices hospitalist medicine in South Florida. He is also the Owner and Medical Director of Integra Functional Internal Medicine. He is interested in mitochondrial function, mitochondrial dysfunction, cancer, cancer as a mitochondrial metabolic disease, can

cer as a metabolic disease, ketogenic metabolic therapy, metabolic therapy, photobiomodulation, integrative medicine, functional medicine, nutrition, biohacking, and quantum biology. Press-Pulse Implementation Lab: https://www.skool.com/press-pulse-implementation-lab-3118/about

25/07/2026

Interesting research highlights that tumor fatty acid type and compartment pH both significantly impact outcomes. Exposure to fatty acids at different pH levels reveals their role in oxidative stress accumulation.

24/07/2026

Not all fats affect cancer cells equally. Some resist oxidation, while others are vulnerable to membrane damage that can trigger cell death (ferroptosis). Could different fat compositions in ketogenic diets significantly alter tumor biology? Let's explore how saturated, monounsaturated, and polyunsaturated fats may influence ferroptosis and boost cancer ketogenic diets.

23/07/2026

A 2021 study reveals that tumor acidosis, often linked to disease progression, actually promotes fatty acid metabolism in cancer cells. Researchers explored if increasing fatty acid uptake could fight tumors. Remarkably, both Omega-3 and Omega-6 polyunsaturated fatty acids selectively induced ferroptosis, a form of cell death, in cancer cells within an acidic environment.

22/07/2026

A critical look at ferroptosis and how compounds like sulfasalazine, artesunate, and statins can be strategically combined to enhance therapies like radiotherapy. Discover the levers to maximize its occurrence in cancer cells for better treatment outcomes.

21/07/2026

This 2022 paper explores ferroptosis, an iron-dependent cell death triggered by lipid peroxide buildup. Unlike other cell death forms, ferroptosis offers unique potential for cancer treatment.

20/07/2026

Discover how PUFA fatty acid synthesis impacts iron metabolism, leading to reactive oxygen species, lipid peroxidation, and ferroptosis. Learn about crucial endogenous antioxidant systems like glutathione and CoQ10 that protect against cell damage.

19/07/2026

Activating ferroptosis in cancer cells is a key goal. We're targeting systems to make cancer cells highly sensitive to therapies. This involves modulating iron import and utilizing mitochondrial metabolism to create a fenton reaction, leading to potent cell death.

18/07/2026

Mitochondrial ROS are crucial for initiating lipid peroxidation and ferroptosis. Electron leakage from complexes I and III generates superoxides, converted to hydrogen peroxide. This, with labile iron, forms hydroxyl radicals driving PUFA-PL peroxidation. Mitochondrial activity also supports ATP production, further promoting ferroptosis.

17/07/2026

Ferroptosis, a unique form of cell death driven by iron and lipid peroxides, is emerging as a potent tumor suppressor. This mechanism shows particular promise against cancer cells that resist traditional therapies, offering new hope for treating refractory cancers.

16/07/2026

Beyond apoptosis and necrosis, a new regulated cell death method called ferroptosis is emerging. It overwhelms cancer cells with oxidative stress, relying on iron, fatty acids, and lipid peroxidation when antioxidant defenses fail.

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Miramar, FL

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