06/06/2026
🧠 CASE SCENARIO OF THE DAY
A 42-year-old male presents to the ED with fever, productive cough, weakness, and progressive shortness of breath.
Past Medical History:
• HIV positive
• Noncompliant with antiretroviral therapy for approximately 1 year
ED Findings:
• Temp 102.8°F
• HR 124
• RR 30
• BP 84/46
• SpO₂ 86% on room air
Labs:
• WBC 2.9
• Lactate 5.6
• Creatinine 2.1 (baseline 0.😎
• Procalcitonin 18.4
• CD4 count 123
• HIV Viral Load 875,000 copies/mL
Imaging:
CT Chest shows bilateral diffuse ground-glass infiltrates concerning for opportunistic pneumonia.
Treatment:
• Broad-spectrum IV antibiotics
• Aggressive IV fluid resuscitation
• Vasopressor support
• High-flow nasal cannula oxygen
Provider Documentation:
• Sepsis due to pneumonia
• Acute hypoxic respiratory failure
• Acute kidney injury
• HIV positive
• Noncompliant with HIV medications
Hospital Course:
Infectious Disease documents:
• HIV + with severe immunosuppression
• Suspected opportunistic infection
• Pneumocystis jirovecii pneumonia (PJP/PCP) cannot be ruled out
💥 CDI OPPORTUNITY:
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