Annals of Internal Medicine

Annals of Internal Medicine Annals of Internal Medicine is the flagship medical journal of the American College of Physicians.

Trending now at Annals.org: Researchers from Columbia University Irving Medical Center found that reducing sleep by just...
08/13/2026

Trending now at Annals.org: Researchers from Columbia University Irving Medical Center found that reducing sleep by just 1.5 hours per night for six weeks was associated with modest increases in body weight, waist circumference, and sedentary time among adults with elevated cardiometabolic risk. https://bit.ly/3UvwAyA

08/13/2026

An outbreak of Vibrio vulnificus, a flesh-eating bacterium commonly found in warm water, has killed five people in Louisiana. A recent case report details an immunosuppressed man who became infected with Vibrio vulnificus after sustaining a scratch from his dog, which had been swimming in warm coastal water.

Following surgery and antibiotics, the man recovered after 23 days. This case not only highlights an unconventional transmission route of Vibrio vulnificus, but it also emphasizes the importance of rapid diagnosis and treatment of high-risk patients. https://bit.ly/45Tiolo

In a new Annals feature, a general internal medicine physician and a cardiologist debate how to manage the case of an ...
08/13/2026

In a new Annals feature, a general internal medicine physician and a cardiologist debate how to manage the case of an 80-year-old man with multiple cardiopulmonary conditions and other organ system comorbidities who is scheduled to undergo extensive skin cancer surgery. This feature is based on a presentation at the American College of Physicians (ACP) Internal Medicine Meeting in April 2026. Read here: https://bit.ly/4hQvLdF

The latest I.M. Matters News feature discusses the American College of Physicians (ACP)’s new series of microgrants desi...
08/12/2026

The latest I.M. Matters News feature discusses the American College of Physicians (ACP)’s new series of microgrants designed to allow front-line clinicians to take a leadership role in addressing in their current settings. The initiative reflects a growing effort to make obesity care more accessible and routine by recognizing obesity's role in numerous chronic health conditions. Read here: https://bit.ly/4wo8mUk

When adults with intellectual and developmental disabilities make medical decisions, supporters can play an important ro...
08/12/2026

When adults with intellectual and developmental disabilities make medical decisions, supporters can play an important role. But how can clinicians ensure the patient's own perspective remains central? A new commentary presents two hypothetical cases to provide context for an ethical framework that can be used to structure patient-centered decision making. https://bit.ly/4zdt37X

In a target trial emulation of patients with and mitral stenosis (AF-MS), researchers found that direct oral (DOAC) ...
08/12/2026

In a target trial emulation of patients with and mitral stenosis (AF-MS), researchers found that direct oral (DOAC) use was associated with a higher risk of stroke within one year compared with warfarin. The findings highlight the need for careful treatment decisions and further research as interest grows in using DOACs as an alternative to for patients with AF-MS. https://bit.ly/4x0LZ8A

Use this free patient summary to help explain the findings of a new randomized trial evaluating joint fusion surgery ver...
08/11/2026

Use this free patient summary to help explain the findings of a new randomized trial evaluating joint fusion surgery versus watchful waiting for patients with painful hallux rigidus. https://bit.ly/45m1b3X

A new Annals feature outlines evidence-based strategies for health care maintenance in the outpatient management of ad...
08/11/2026

A new Annals feature outlines evidence-based strategies for health care maintenance in the outpatient management of adults with . https://bit.ly/4xtJmMk

A randomized trial found that patients with painful hallux rigidus ( of the big toe joint) who underwent first metatars...
08/11/2026

A randomized trial found that patients with painful hallux rigidus ( of the big toe joint) who underwent first metatarsophalangeal joint (MTPJ) arthrodesis reported substantially less walking pain after 12 months compared with watchful waiting. The findings reinforce joint fusion as the preferred treatment for some patients with painful hallux rigidus. https://bit.ly/4zg20Ju

Five people in Louisiana have died from Vibrio vulnificus, a flesh-eating bacterium that thrives in warm, brackish water...
08/10/2026

Five people in Louisiana have died from Vibrio vulnificus, a flesh-eating bacterium that thrives in warm, brackish water. While typically associated with the Southeastern U.S. coast, a case report from the Annals of Internal Medicine archives describes 5 infections in the Delaware Bay area, highlighting the bacterium's expanding range as sea temperatures rise. Clinicians should remain aware of its symptoms and treatment as climate change alters seasonal windows for bacteria in marine ecosystems. https://bit.ly/3RKCYRQ

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