theNNT.com

24/04/2026

https://thennt.com/nnt/sustained-release-naltrexone-for-opioid-dependence/

Sustained-release naltrexone reduces illicit opioid use compared to standard care but shows slightly worse outcomes than opioid agonists

20/04/2026

This is a brief but deeply affecting piece that invites physicians to be mindful of how they balance commitment to medicine with their own well-being. Worth reading not just for its clinical perspective, but for highlighting what truly matters when that balance is suddenly challenged.

In this narrative medicine essay, a psychiatrist and residency program director discusses how her lung cancer diagnosis caused her to shift her priorities regarding work and home life.

01/04/2026

https://thennt.com/nnt/higher-versus-lower-mean-arterial-blood-pressure-targets-in-vasodilatory-shock/

26/03/2026

https://www.acep.org/news/acep-newsroom-articles/2-2-26-acep-will-not-endorse-new-sepsis-guidelines-from-the-surviving-sepsis-campaign #:~:text=The%20decision%20to%20not%20endorse,patients%20in%20the%20emergency%20department%2C

After a thorough and comprehensive review by a panel of experts convened from the membership of the College, the American College of Emergency Physicians (ACEP) today informed the Surviving Sepsis Campaign (SSC) that ACEP will not endorse the organization’s latest update to guidelines for treatmen...

24/03/2026

"The failure of vitamin C supplementation to reduce the incidence of colds in the general population indicates that routine vitamin C supplementation is not justified"

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24/03/2026

https://jamanetwork.com/journals/jama/fullarticle/2844116?guestAccessKey=0d7f20b5-a2e0-48c8-94c9-cee3a1efb051&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jama&utm_content=etoc-tfl_&utm_term=032426

This observational follow-up of patients in the Appendicitis Acuta multicenter randomized clinical trial conducted in Finland assesses the 10-year appendicitis recurrence and appendectomy rate in adult patients with uncomplicated appendicitis treated with antibiotics.

16/03/2026

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25/02/2026

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23/02/2026

https://thennt.com/nnt/extracorporeal-cardiopulmonary-resuscitation-for-refractory-out-of-hospital-cardiac-arrest/

12/02/2026

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