03/10/2025
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Six Clinically Recognizable Pain Distribution Patterns in Lumbar Spinal Stenosis
■ 🧩 Overview
Based on a study of 2,379 patients with lumbar spinal stenosis (LSS) presenting to a secondary spine center in Denmark, six clinically recognizable pain distribution patterns were identified using digital pain diagrams.
These findings highlight that heterogeneous pain presentations are common in people with LSS and that pain distribution is often more complex than the "textbook" presentations of central or lateral stenosis.
■ 🔹 Class 1: Bilateral posterior leg pain
This pattern was present in 11.4% of the patients (n=272).
It represents pain located in the back of both legs.
This distribution is often considered a "textbook" LSS pain pattern associated with central canal stenosis, where multiple nerve roots are involved.
■ 🔹 Class 2: Bilateral posterior and anterior leg pain
This pattern was identified in 8.7% of patients (n=207).
It involves pain in both the front and back of both legs.
The presence of anterior leg pain in a bilateral pattern illustrates a more complex pain presentation than is typically described.
■ 🔹 Class 3: Unilateral posterior leg pain
This was the most common pattern, found in 26.1% of the patients (n=620).
This class describes pain in the back of a single leg and is often associated with lateral stenosis affecting a single nerve root.
The researchers specifically distinguished this class from Class 4 to highlight the difference between unilateral posterior leg pain with and without a focus on low back pain.
■ 🔹 Class 4: Unilateral posterior leg pain with low back pain
This pattern accounted for 21.0% of the patient sample (n=499).
While other classes also included patients with back pain, this class was named to specifically highlight the combination of unilateral posterior leg pain and low back pain.
Patients in this group reported slightly lower mean leg pain scores compared to the other classes.
■ 🔹 Class 5: Unilateral anterior and posterior leg pain
This pattern was identified in 22.9% of patients (n=545).
It describes pain in both the front and back of a single leg.
The study notes that the proportion of patients with this pattern was greater than the combined proportion of patients with both types of bilateral leg pain (Class 1 and Class 2), underscoring the significant heterogeneity in LSS pain presentations.
■ 🔹 Class 6: Multisite pain
This pattern was found in 9.9% of patients (n=236).
This class had a higher proportion of females (58.9%) than other groups.
Patients in this group also reported slightly greater social isolation scores and were more likely to have experienced pain for more than 12 months.
The identification of this pattern may help clinicians differentiate LSS from other conditions, such as multi-joint osteoarthritis.
■ 🩺 Clinical Relevance
These identified pain distribution patterns may represent clinical LSS phenotypes that could help improve diagnosis, patient-clinician communication, and treatment decisions.
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