20/12/2025
💊 Drugs of choice in hypertension
🔹 Primary (essential) hypertension
• Thiazides
• ACE inhibitors / ARBs
• Calcium channel blockers
🧠 Mnemonic: TAC
→ Thiazide – ACE/ARB – CCB
🔹 Hypertension + diabetes
• ACE inhibitors / ARBs (renal protection)
• CCBs
• Thiazides
• β-blockers
🧠 Mnemonic: “D-ACE protects kidneys”
🔹 Hypertension + pregnancy
• Hydralazine
• Methyldopa
• Labetalol
• Nifedipine
🧠 Mnemonic: “Hi Mom Loves Nifedipine” (HMLN)
🔹 Hypertension + heart failure
• ACE inhibitors / ARBs
• β-blockers (only if stable)
• Aldosterone antagonists
• Diuretics
🧠 Mnemonic: “BAD for HF (but good!)”
→ Beta-blocker, ACE/ARB, Diuretic
🔹 Hypertension + asthma
• ARBs
• CCBs
• Thiazides
• Cardioselective β-blockers
🧠 Mnemonic: “ABC safe for Asthma”
→ ARB, B1-selective, CCB
🚫 Avoid non-selective β-blockers
🔹 Hypertension + osteoporosis
• Thiazides (↑ Ca²⁺ retention)
🧠 Mnemonic: “THIAZIDE saves THIN bones”
🔹 Hypertension + gout
• ACE inhibitors
• CCBs
• ARBs (losartan best)
🧠 Mnemonic: “LOSA-TAN lowers uric acid”
🚫 Avoid thiazides & loop diuretics