18/09/2026
We tend to think about fructose in terms of sugar, calories and weight.
But thereâs another part of the story: what happens inside your mitochondria.
In this clip, Chris Mearns explains how fructose metabolism can trigger a cascade involving ATP depletion, uric acid and oxidative stress â potentially signalling the cell to conserve energy rather than burn it.
And when your mitochondria are the engines driving cellular energy, thatâs a conversation worth having.
This is one of my favourite moments from our discussion because it takes the fructose debate far beyond âsugar is badâ.
Would you have guessed fructose could affect mitochondrial function?
Comment âCHRISâ and weâll DM you the link to the full episode.