04/08/2026
Did you know hypermobility and mast cell activation often occur together?
Mast cells live within your connective tissue. When connective tissue is more flexible, mast cells may be easier to activate. This may help explain why so many people experience joint pain, dizziness, palpitations, gut symptoms, bladder symptoms, headaches, easy bruising and widespread sensitivity alongside hypermobility.
We’re still learning why these conditions overlap, but recognising the connection can help make sense of symptoms that once seemed completely unrelated.
This is Episode 3 of my MCAS Basics series. Follow for the next episode as we continue connecting the dots.