Osteoarthritis Clinical Research Group

27/07/2026

We conducted a 12-week double blind, randomised, placebo-trial investigating an oral complementary medicine for symptomatic knee .

🌿 We found that the complementary medicine combination containing boswellia serrata extract 250 mg, pine bark extract 100 mg, methylsulfonylmethane 1500 mg, curcumin 500 mg, and piperine 5 mg was not superior to placebo for improving pain over 12 weeks.

🚫 The evidence does not support the use of this combination to treat people with knee osteoarthritis.

Read the full paper in Osteoarthritis and Cartilage Journal
🔗 https://www.oarsijournal.com/article/S1063-4584(26)00950-7/fulltext

12/07/2026

The right shoe can make a real difference for people living with knee osteoarthritis, but knowing what to look for isn't always straightforward. 👟

This week on the Joint Action podcast, Professor David Hunter sits down with A/Prof Kade Paterson, whose research is helping us understand exactly how footwear affects knee load and pain.

Whether you are a clinician advising patients or someone managing OA day to day, this one has practical takeaways.

🎧 Listen at www.jointaction.info/podcast or on your favourite podcast player!

01/06/2026

🦵 What if you could prevent knee osteoarthritis before it starts?

We sat down with the scientists and behaviour change experts behind TOPS — a groundbreaking clinical trial designed to help women build the lasting lifestyle habits that protect their joints.

Prof. David Hunter, Prof. Stephen Messier, Shannon Mihalko, Monica Love, and Emily Williamson break down the science of habit formation, what’s driving this research, and why empowering women to take control of their health matters worldwide 🌏

💬 Comment TOPS below and we’ll DM you the exclusive link to watch the full discussion 👇 OR to join the study click on out overview page: https://www.osteoarthritisresearch.com.au/tops-study-overview

01/06/2026

"Hear from Frances, our TOPS Project Manager! 🌟 We love seeing the real impact the TOPS study is having on women's health and wellbeing at the University of Sydney. "

26/05/2026

🦵 What if you could prevent knee osteoarthritis?

We sat down with the scientists and interventionalists behind TOPS — a groundbreaking clinical trial exploring exactly that.

Prof. David Hunter, Prof. Stephen Messier, Shannon Mihalko, Monica Love and Emily Williamson share what’s driving this research and why it matters for millions of women worldwide 🌏

💬 Comment TOPS below and we’ll DM you the exclusive link to watch 👇

25/05/2026

Healthy Joints - Let's Walk This Journey Together 🦴✨

The Osteoarthritis Clinical Research Group 2026 Strategic Planning Session brought together our dedicated team of academics, researchers, and professional staff in osteoarthritis clinical research.

Led by Professor David Hunter, we aligned our 2026 research priorities and identified strategic opportunities that deepen the interdisciplinary collaborations that power world-class osteoarthritis research, care and innovation.

Together, we are advancing joint health research- one step at a time.

13/05/2026

Our TOPS study is still recruiting women over the age of 50 who want to improve their joint health, make friends, and boost confidence! 🏋🏻‍♀️🍎🚶🏻‍♀️

➡️ Classes are now open Monday and Wednesday 4-6pm in Parramatta as well as Tuesday and Thursdays morning and evening times at Royal North Shore Hospital.

Click our link in bio to find out more! 😊

23/03/2026

At last week's team meeting we had the pleasure of hearing from Mijin Jung, a post-doctoral researcher visiting us from The University of Bristol.

🩻 Mijin presented on her work investigating knee alignment and risk of osteoarthritis using data from the UK Biobank.

💊 Joce also presented an update on the ATLAS study investigating a combination of supplement containing Boswellia serrata extract, pine bark extract, methylsulfonylmethane, piperine and curcumin and the results of her systematic review.

31/10/2025

🌟 Our team was thrilled to connect with the Lane Cove community through Lane Cove Council to share insights on how diet and exercise play a vital role in managing osteoarthritis. Empowering people with knowledge is the first step toward healthier, more active lives! 💪
Lane Cove - Community Group cove council 🥗🧘‍♀️

21/10/2025

Our clinical research team, led by Professor David Hunter, is looking for people to join the CASCADE-OA trial. The trial goes for 12-months and is testing whether a physical activity program designed for people with hip/knee osteoarthritis can help you keep active.

Participants will:
💙 Get a FREE Fitbit to keep
💙 Have access to a free physical activity program especially designed for people with knee/hip osteoarthritis
💙 Help improve our understanding of keeping active with . You may also feel improvements in your joint pain.

Visit https://www.osteoarthritisresearch.com.au/cascadeoa-study-overview to learn more about the CASCADE-OA study and check your eligibility!

The University of Sydney’s CASCADE-OA study is testing and researching a new intervention for knee osteoarthritis.