30/07/2026
Some scars remain raised, red, itchy, and uncomfortable long after healing appears complete, and the nervous system may be part of the reason why.
In hypertrophic scars, an increase in nerve fibres carrying accumulated neuropeptides has been observed — a process believed to be stimulated by abnormal tension originating from the injured site.
These neuroinflammatory signals may prolong the production of growth factors and cytokines, leading to an excess of extracellular matrix and ongoing collagen deposition within the scar tissue.
This helps explain why hypertrophic scars can feel as symptomatic as they look — and why addressing mechanical tension is not just a structural concern, but a neurological one.
The itch, the discomfort, and the continued growth of a hypertrophic scar may all reflect the same underlying process: a nervous system responding to unresolved tension in the healing tissue.