05/28/2026
NEW ARTICLE: RESEARCH: IV**MECTIN in RHEUMATOID ARTHRITIS - 2023 Paper from Pakistan
What about Iv**mectin and Rheumatoid Arthritis?
2023 Khan et al - Evaluation of therapeutic potential of iv**mectin against complete Freund's adjuvant-induced arthritis in rats: Involvement of inflammatory mediators
HIGHLIGHTS:
32 male Wistar rats were randomly divided into four groups: control, diseased, dexamethasone, and iv**mectin groups
After 7 days of rheumatoid arthritis induction, animals were treated with dexamethasone (steroid) 5 mg/kg and Ivermectin 6 mg/kg
RESULTS:
Iv**mectin has no significant effect on the body weight of rats. Rat's body weight decreased in the diseased group.
On Day 15 of the study, there was a significant decrease in arthritis in the dexamethasone and iv**mectin groups in comparison with the diseased group
there was significant increase in WBC count in the diseased groups
After the treatment, the WBC count was significantly decreased in the dexamethasone and Iv**mectin groups
There was highly significant subcutaneous inflammation, synovial inflammation, and bone erosion in the diseased group as compared with the control group
Inflammation in the Iv**mectin group decreased moderately and significantly as compared with the diseased group
Bone erosion, cartilage erosion, pannus formation were decreased significantly in the Iv**mectin group
CONCLUSION:
"In our study, results showed that iv**mectin improved the histopathological characteristics in comparison with the diseased group"
"Ultimate aim of using ivermectin was to preserve the tissue architecture, morphology, and function. Histological data suggest that it has succeeded in protecting bone and joint articulation to some extent by preventing the influx of inflammatory cells, as well as the differentiation and proliferation of osteoclasts within the joint cavity."
"Our study has demonstrated that iv**mectin does have anti-inflammatory and antiarthritic effects that are in some cases comparable with those of the potent corticosteroid dexamethasone." (!!)
Iv**mectin increased body weight, improved the visual arthritic score, and decreased WBC, neutrophils, and lymphocytes counts.
Iv**mectin also decreased the expression of inflammatory cytokines, TLR-2, TNF, IL-17, and NF-κB
Now you can see why Big Pharma fears Iv**mectin so much 😃
Iv**mectin research shows impressive Iv**mectin activity not only against viruses, but also against cancer and autoimmune diseases.
I have helped over 9000 people with repurposed drugs: Iv**mectin, Mebenda**le and Fenbenda**le.
A small subset of the 9000 had autoimmune diseases including Rheumatoid Arthritis.