12/01/2023
While there is research on Natural Desiccated Thyroid (NDT) use, there aren’t a lot of studies directly comparing it to Synthroid. However, the few that we have are favourable.
In a recent study, 6 months after switching to NDT from levothyroxine, the study participants reported improvement in symptoms across all domains surveyed which included improvement in “𝐞𝐧𝐞𝐫𝐠𝐲, 𝐫𝐞𝐬𝐨𝐥𝐮𝐭𝐢𝐨𝐧 𝐨𝐟 𝐛𝐫𝐚𝐢𝐧 𝐟𝐨𝐠, 𝐢𝐦𝐩𝐫𝐨𝐯𝐞𝐝 𝐬𝐥𝐞𝐞𝐩 𝐩𝐚𝐭𝐭𝐞𝐫𝐧𝐬, 𝐟𝐞𝐞𝐥𝐢𝐧𝐠 𝐦𝐨𝐫𝐞 𝐚𝐥𝐞𝐫𝐭 𝐚𝐧𝐝 𝐬𝐭𝐫𝐨𝐧𝐠𝐞𝐫, 𝐥𝐢𝐟𝐭𝐢𝐧𝐠 𝐨𝐟 𝐝𝐞𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧, 𝐫𝐞𝐝𝐮𝐜𝐭𝐢𝐨𝐧 𝐢𝐧 𝐚𝐧𝐱𝐢𝐞𝐭𝐲 𝐚𝐧𝐝 𝐭𝐞𝐧𝐬𝐢𝐨𝐧 𝐚𝐧𝐝 𝐢𝐦𝐩𝐫𝐨𝐯𝐞𝐝 𝐯𝐢𝐠𝐨𝐮𝐫/𝐬𝐭𝐫𝐞𝐧𝐠𝐭𝐡.” Significant symptomatic benefits and improvement in quality of life were experienced by patients with a history of hypothyroidism unresponsive to levothyroxine when treated with NDT.
📝PMID: 34626513
In a study comparing NDT to T4 (levothyroxine) 48% preferred NDT, 18% preferred T4, and 32% had no preference. The study participants reported having 𝐛𝐞𝐭𝐭𝐞𝐫 𝐞𝐧𝐞𝐫𝐠𝐲, 𝐰𝐞𝐢𝐠𝐡𝐭 𝐥𝐨𝐬𝐬, 𝐢𝐦𝐩𝐫𝐨𝐯𝐞𝐝 𝐜𝐨𝐠𝐧𝐢𝐭𝐢𝐨𝐧, 𝐚𝐧𝐝 𝐦𝐨𝐨𝐝 with NDT. The patients most symptomatic on T4 medication preferred and responded favourably to NDT.
📝 PMID: 23539727
NDT isn’t the full solution when it comes to comprehensive thyroid care, but from a
medication-only standpoint, many patients notice improvements and prefer NDT when given the choice.