Pagdin Health

Pagdin Health KELOWNA, BC - The official page of Pagdin Health. Anti-Aging & Regenerative Medicine. KELOWNA, BC - The official page of Dr. Grant Pagdin.

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09/01/2026

The biggest misconception about regenerative medicine is that it can fix anything.

It cannot. And any clinic that tells you otherwise is selling, not assessing.

At our private clinic in Kelowna, the conversation starts somewhere else entirely. Before we talk about any procedure, we weigh three things:

• What is the specific problem you are dealing with
• What the clinical picture actually shows
• Which approach, if any, is a reasonable fit

Only then do we discuss what the right ingredients might be to help address that problem.

A lot of the advice online comes from marketing, not medical research. It treats regenerative medicine like a single product with a single answer. Real practice looks nothing like that. Two people can walk in with the same complaint and leave with two completely different plans, because their history, their imaging and their goals are different.

That is the point of a physician-led assessment. Not a preset menu. A decision built around you.

If you have been reading about regenerative options and are not sure where you fit, book a conversation. We will tell you plainly whether it makes clinical sense.

08/16/2026

Going through a little “cougar puberty” of your own? 😅🔥

Hot flashes, mood changes, sleep struggles, brain fog, low energy… menopause and perimenopause can sometimes feel like puberty decided to make a comeback.

The good news? You don’t have to just tough it out. Our team at Pagdin Health can help you explore whether BHRT (Bioidentical Hormone Replacement Therapy) may be right for you.

Cute video aside — we’ve got your back. 💚

Book an Evaluation with our team today and let’s talk about what you’re experiencing.



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08/12/2026

Mitochondrial health doesn't come from a single compound — here's how we think about the full picture. ⚡

When we're building a comprehensive mitochondrial support protocol at our Kelowna clinic, we consider four key compounds working synergistically:

🔵 Methylene Blue — supports electron transport chain function, reduces beta-amyloid
🧬 MOTS-C — broad mitochondrial ATP production, metabolic efficiency
⚡ SS31 — inner membrane cardiolipin binding, targeted oxidative protection
🌿 CoQ10 and Magnesium (citrate/malate) — essential cofactors for the electron transport chain and ATP synthesis

CoQ10 and magnesium aren't optional add-ons. ATP synthesis literally cannot proceed without them in adequate amounts. They're foundational to the same machinery the peptides are supporting.

The goal is building a protocol where every compound earns its place — not stacking for the sake of complexity. Our physician-led approach means we individualize which elements are appropriate and at what doses based on your health history, bloodwork, and goals.

08/11/2026

IT’S YOUR HORMONES!!!! 😅🔥

A little humour, but a very real topic.

If perimenopause or menopause has you feeling like your body suddenly changed the rules, you’re definitely not alone.

At Pagdin Health, we help women understand what’s going on and explore whether BHRT may be right for them.

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08/07/2026

A 70% increase in collagen production — here's the mechanism. 🔬

GHK-Cu works on collagen at the enzymatic level. It activates lysyl oxidase — the copper-dependent enzyme responsible for cross-linking collagen fibres. Without that cross-linking, collagen structure is weak. With it, you get durable, organized connective tissue.

The result: GHK-Cu can drive up to a 70% increase in collagen production. But it doesn't stop there. The same mechanism influences elastin and glycosaminoglycans — the building blocks of supple, resilient skin.

Beyond structural proteins, GHK-Cu affects the expression of multiple growth factors: fibroblast growth factor (FGF), vascular endothelial growth factor (VEGF), and others. As a small molecule with the ability to influence gene expression, its regenerative reach extends well beyond surface aesthetics.

This is why we consider high-concentration compounded GHK-Cu a genuinely therapeutic tool — not a cosmetic ingredient.

08/05/2026

The difference between cosmetic copper and clinical copper peptide is concentration. 🔬

While small amounts of GHK-Cu have appeared in medical-grade cosmetics for years, a product formulated at a therapeutically meaningful concentration simply wasn't available — until compounding made it possible.

At our Kelowna clinic, we offer high-concentration GHK-Cu that goes well beyond what you'll find in commercial skin care. The mechanism is structural: GHK-Cu helps regenerate the architecture of your skin and hair follicles. This means we can use it to genuinely remodel the skin — not just moisturize or temporarily plump it — and to stimulate natural, permanent hair growth by addressing the follicular environment directly.

This is a meaningful distinction. Most cosmetic products use GHK-Cu as a minor ingredient for marketing purposes. What we offer is a clinically concentrated formulation with a defined biological target.

Decisions are based on your skin health, goals, and what we're trying to achieve — because when it comes to something this specific, one-size-fits-all doesn't work.

07/29/2026

The format of your GHK-Cu matters as much as the concentration. Here's how we think about it. 💆

At our Kelowna clinic, GHK-Cu is available in two formats:

The cosmetic base — a cream-like moisturizer — is ideal for facial application, targeting the skin's surface with a familiar, easy-to-apply texture. Some patients also use this format directly on their hairline, working it into the edge of the scalp where they prefer the feel of a cream over a liquid.

The foam formulation is designed for scalp application — specifically for reaching the scalp beneath existing hair. The liquid consistency allows it to be worked through the hair and contact the scalp directly, which is critical for stimulating follicle growth where hair is still present. For areas like the back of the head or wherever you need to access the scalp beneath coverage, the foam is simply more effective.

We match the format to where you're trying to drive results.

07/22/2026

SS31 is one of the most targeted mitochondrial compounds we use — here's what it's actually doing. 🔬

SS31 selectively binds to cardiolipin — a phospholipid located exclusively on the inner mitochondrial membrane. By binding there, it stabilizes the electron transport chain complexes, preventing the dysfunction that leads to mitochondrial resistance and declining energy production.

The downstream effects:
- Improved mitochondrial function
- Supported mitogenesis (formation of new mitochondria)
- Enhanced ATP production
- Reduced reactive oxygen species (ROS) during ATP synthesis
- Active scavenging of superoxide, hydrogen peroxide, peroxynitrite, and hydroxyl radical

That last point makes SS31 an exceptional antioxidant — but one that operates precisely where the damage happens, rather than broadly throughout the body.

As an antioxidant with inner-membrane specificity, SS31 is in a different category from generalized antioxidant supplementation. This is exactly why physician-led longevity medicine can produce results that are simply not achievable through over-the-counter supplements.

07/21/2026

The best hair restoration protocols combine proven ingredients — not just one. 🧬

At our Kelowna clinic, our compounding pharmacy can formulate GHK-Cu with a range of complementary ingredients to create a targeted hair restoration product. Minoxidil is the most common combination — and often finasteride as well.

One important nuance our pharmacists advise: if the ingredient list gets too long, we recommend splitting into two separate products. Diluting GHK-Cu by adding too many actives in the same formulation can reduce its effective concentration — and that defeats the purpose.

Our goal is to design a protocol where each ingredient works at the concentration it needs to.

Hair restoration at our clinic isn't a one-size-fits-all solution. We look at your specific pattern, health history, hormonal picture, and what your follicles actually need — then design the right formulation strategy around that.

07/17/2026

Good news for patients interested in SS31 and MOTS-C: access is expanding. 🔬

MOTS-C is currently available through compounding pharmacies. SS31 (also known as elamipretide or Bendavia in the US) has an approved brand name for the treatment of Barth syndrome — which means it can be used off-label for other indications under physician supervision. However, the brand-name product comes at a premium, and SS31 is now also moving into compounding pathways, which should bring the cost down significantly.

Off-label use of an approved drug is quite different from using a non-approved compound — it's a recognized and established practice in medicine when the physician has clinical rationale for its use.

At our clinic in Kelowna, we work with regulated Canadian compounding pharmacies for MOTS-C and monitor the availability of SS31 through both pathways. As access evolves, we ensure our patients can benefit from these advances in a properly supervised, physician-led setting.

Address

#1-1131 Lawson Avenue
Kelowna, BC
V1Y6T8

Opening Hours

Monday 8am - 4:30pm
Tuesday 8am - 4pm
Wednesday 8am - 4pm
Thursday 8am - 4pm
Friday 8am - 4pm

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