Cannabis Science Information

09/10/2026

Deconstruction of lysergic acid diethylamide

Lysergic acid diethylamide (L*D) is perhaps the best-known psychedelic and is currently being explored as a treatment for neuropsychiatric diseases. Despite being discovered over 8 decades ago, we have an incomplete understanding of how its molecular structure produces its unique pharmacological effects as structure–activity relationship studies have been hindered by the complexity of its tetracyclic ergoline core structure.

Of the classic psychedelics, lysergic acid diethylamide (L*D) is perhaps the best-known, but its complex chemical architecture has limited syntheti...

09/09/2026

Delta9-tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism

09/08/2026

Δ9-Tetrahydrocannabinol induces apoptosis in C6 glioma cells
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Δ9-Tetrahydrocannabinol (THC), the major active component of ma*****na, induced apoptosis in C6.9 glioma cells, as determined by DNA fragmentation and loss of plasma membrane asymmetry. THC stimulate...

09/07/2026

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cannabinoids seem to be selective antitumoral compounds, as they kill glioma cells, but not their non-transformed astroglial counterparts.
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09/03/2026

Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes

09/01/2026

Conclusions:
The absence of any differences between the exposed on nonexposed groups in the early neonatal period suggest that the better scores of exposed neonates at 1 month are traceable to the cultural positioning and social and economic characteristics of mothers using ma*****na that select for the use of ma*****na but also promote neonatal development.

08/30/2026

https://www.sciencealert.com/scientists-discover-a-cannabis-receptor-that-could-stop-breast-cancer-spreading

Cancer cells are proving trickier than we thought, so scientists are getting even trickier to shift the survival odds in our favor. Recent medical research has highlighted a significant issue: cancer cells display plasticity.  Some cancer cells can spontaneously revert from a differentiated state t...

08/27/2026

I can personably attest to the extreme safety and efficacy of Cannabinoid Therapy in treating Osteoarthritis pain and inflammation.

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Increasing evidence from preclinical studies supports the interest of the endocannabinoid system as an emerging therapeutic target for osteoarthritis pain. Indeed, pharmacological studies have shown the anti-nociceptive effects of cannabinoids in different rodent models of osteoarthritis, and compelling evidence suggests an active participation of the endocannabinoid system in the pathophysiology of this disease.
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08/25/2026

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study