06/08/2026
A recent Frontiers in Neuroscience case report described temporary improvements in an 80-year-old woman with advanced Alzheimer’s disease after psilocybin administration.
Researchers reported changes across several functions, including speech, social interaction, continence, movement, and memory recall, but they clearly cautioned that this does not prove disease reversal.
The finding is important because Alzheimer’s can leave some abilities inaccessible rather than completely erased, raising questions about whether certain brain networks can be briefly reactivated.
Psilocybin is being studied because it affects serotonin receptors and may influence neuroplasticity, mood, inflammation, and communication between brain regions.
This remains a single-patient case, not a proven treatment, so larger controlled clinical trials are needed before anyone can call it a safe or effective Alzheimer’s therapy.