The Accudopa Project

The Accudopa Project Finding better ways to live with levodopa. We’ve seen exciting early success and publication of our results is underway.

I’m a health modeller passionate about making life better for those with Parkinson’s disease, dopa-responsive dystonia, and other levodopa-responsive conditions. If you have one of these conditions, are a caregiver, or are a medical practitioner dealing with levodopa, you’re in the right place — welcome! Since 2024 I’ve been developing a tool to help pharmacists, clinicians, and specialists optimi

ze levodopa doses and schedules based on individual needs and symptoms. Your support will directly fund scientific research, help refine our tools, and work towards improving the quality of life for millions who rely on levodopa and dopamine agonists. You’ll also be one of the first to know about open clinical trials involving our work. Disclaimer: I am not a doctor and this page does not offer medical advice. Always talk to qualified members of your care team before making any changes to your medical routine.

Here's a weird Monday fact for you: People with Parkinson's disease frequently have so much iron in their brains that it...
09/07/2026

Here's a weird Monday fact for you: People with Parkinson's disease frequently have so much iron in their brains that it shows up on MRIs -- and it's not clear if it's a cause or symptom. 😬

Today we take a look at the conflicting views and how in 2026 we still don't have a definitive answer!

For decades, MRIs showed iron buildup in the brains of people with Parkinson's. The prevailing idea was simple: because excess iron can caus

Fun fact: one of your favourite fruits might be full of MAO inhibitors. 🫐 Today on Accudopa we discuss which one. Read t...
07/20/2026

Fun fact: one of your favourite fruits might be full of MAO inhibitors. 🫐

Today on Accudopa we discuss which one. Read this freebie to find out more! 👇

Levodopa remains the gold standard for managing Parkinson’s symptoms, but its effectiveness can quickly wane after each dose. As we’ve previ

After a small vacation, we're back!  medication can cause unpleasant side effects, but exercise can help. The question i...
07/09/2026

After a small vacation, we're back!

medication can cause unpleasant side effects, but exercise can help. The question is how much you need, and whether it can reduce your medication requirements.

Today on Accudopa we're exploring what happens if you take daily exercise to its natural extreme.

Exercise can help slow the progression of several levodopa-responsive conditions and make daily life easier. But what happens when you push

  has a reputation for being unpredictable.The data disagrees: use a standard scale and the decline tracks linearly for ...
06/22/2026

has a reputation for being unpredictable.

The data disagrees: use a standard scale and the decline tracks linearly for years. 📊

Today we discuss what that predictability means for treating the condition and planning for its evolution.

Parkinson's disease, especially its medication, has a reputation for being unpredictable. The picture changes with a longer view: research t

I really struggled to find an analogy for this week's math-focussed article, and then it hit me: it's calorie counting. ...
06/04/2026

I really struggled to find an analogy for this week's math-focussed article, and then it hit me: it's calorie counting. I wrote a blog about calorie counting for drugs that let you walk. 😅

(Cue Always Has Been meme? 🧑‍🚀 )

Apples and Oranges: One simple trick to convert everything to levodopa by The Accudopa Project on Patreon. Join The Accudopa Project's community for exclusive content and updates.

Levodopa is the gold standard for Parkinson's... until the side effects leave you needing a plan B.Levodopa, meet agonis...
05/15/2026

Levodopa is the gold standard for Parkinson's... until the side effects leave you needing a plan B.

Levodopa, meet agonists. In this week's Accudopa article, we look at the drugs that mimic dopamine (including the ones that come from fungus.)

A tour of dopamine agonists (including the ones that come from fungus!) by The Accudopa Project on Patreon. Join The Accudopa Project's community for exclusive content and updates.

Last week I attended my first Uniting The Prairies event. It held many lessons for the future of   and for getting it in...
05/06/2026

Last week I attended my first Uniting The Prairies event. It held many lessons for the future of and for getting it into the hands of those who need it. 💡

In this week's post we dive into the key takeaways!

Uniting the Prairies: Lessons Learned from a Major Startup Conference by The Accudopa Project on Patreon. Join The Accudopa Project's community for exclusive content and updates.

Women are underrepresented in   research, especially those of childbearing age. Thankfully, expert guidance on managing ...
04/21/2026

Women are underrepresented in research, especially those of childbearing age.

Thankfully, expert guidance on managing Parkinson's disease during is now available and offers practical advice on a range of topics including medication safety, breastfeeding, and hormone changes.🤰

It's not a complete picture yet, but it's a vital starting point for patients and clinicians alike. 👉

Pregnant with Parkinson's: what we know (and what we don't) by The Accudopa Project on Patreon. Join The Accudopa Project's community for exclusive content and updates.

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