06/19/2026
Using over-the-counter drops to "get the red out" often creates a cycle of chronic ocular irritation known as rebound hyperemia.
Many popular redness-relief medications utilize vasoconstrictors such as Brimonidine or Naphazoline. These chemicals work by temporarily constricting the blood vessels on the surface of the eye to make them appear whiter. However, as the medication wears off, the vessels often dilate significantly more than before, leading to a "pickled" or chronically red appearance that requires more frequent dosing to manage.
The Solution:
• Discontinue the use of drops containing vasoconstrictors for daily redness management.
• Switch to Preservative-Free (PF) artificial tears.
• Focus on addressing the underlying cause of the redness, such as dry eye, environmental allergens, or digital eye strain.
Preservative-free lubricants support the ocular surface and stabilize the tear film without the risk of chemical dependency. This allows the blood vessels to return to their natural state and the ocular surface to heal without inflammatory interference.
Follow for more evidence-based eye and brain health.
PMID: 32673830