08/07/2026
If your child has been diagnosed with PANDAS or PANS, you may have heard about Low-Dose Naltrexone (LDN) as a potential treatment option.
🤔 So, what is it?
🌟 LDN is a medication prescribed in very small doses (typically 0.5–4.5 mg) that helps regulate the immune system and reduce inflammation. Unlike medications that suppress the immune system, LDN works by helping to restore immune balance and may reduce neuroinflammation.
In children with PANDAS/PANS, an abnormal immune response to an infection can trigger inflammation within the brain, leading to a sudden onset of neurological and psychiatric symptoms.
⬇️ LDN may help support ⬇️
- Immune system regulation
- Reduction in neuroinflammation
- OCD symptoms
- Mood regulation - anxiety, panic
- Tics (motor and verbal)
- Irritability and rage episodes
- Sleep quality
- Overall symptom severity
While LDN can be a valuable tool, it is not a standalone treatment. Successful management of PANDAS/PANS often requires addressing the underlying trigger, whether that is an active infection, chronic inflammation, immune dysregulation, gut health, environmental factors, or other contributors.
Every child responds differently, and treatment should always be individualized based on their symptoms, medical history, and underlying drivers.
If you’re wondering whether Low-Dose Naltrexone may be appropriate for your child, Dr. Bri Takesh*ta is happy to discuss whether it could be part of a comprehensive treatment plan. 🌙