01/09/2026
By • In this video, the clinician is positioned over the first premolar, pretty close to the classic AMSA injection site: between the first and second premolars, approximately halfway between the palatal gingival margin and the midpalatal raphe. This location allows the anesthetic to diffuse through the palatal bone and reach the underlying dental plexus.
Why do I like the AMSA?
👉 Broad anesthesia for periodontal therapy: One palatal injection may anesthetize multiple areas of the maxilla.
👉 Less facial numbness: The upper lip and facial muscles are generally not anesthetized.
👉 Palatal coverage: It can anesthetize palatal tissues along with the maxillary teeth and periodontal tissues in the region.
The AMSA may provide anesthesia involving the central and lateral incisors, canine, first and second premolars, and sometimes the mesiobuccal root of the first molar, along with buccal periodontal tissues and palatal gingiva and mucosa. Coverage can vary, so always test and supplement as needed.
Because the palate is tightly bound to the underlying tissue, slow delivery is essential. Published protocols commonly use approximately 0.6–0.9 mL, deposited at about 0.5 mL per minute.
How often do you use the AMSA?