Chinese Medical Journal

Chinese Medical Journal As the official journal of Chinese Medical Association, CMJ is an international peer-reviewed genera

Neurological diseases are a growing health challenge in China.Stroke (including intracerebral hemorrhage and ischemic st...
25/05/2026

Neurological diseases are a growing health challenge in China.
Stroke (including intracerebral hemorrhage and ischemic stroke) and dementia lead the burden, with dementia and Parkinson’s increasing the fastest. The impact varies by age, gender, and region.

High blood pressure and lifestyle risks like smoking, alcohol use, and low physical activity are key drivers.

Prevention and early intervention are more important than ever.

Read more: https://journals.lww.com/cmj/fulltext/9900/prevalence_and_burden_of_neurological_diseases_in.2001.aspx

Male infertility is emerging as a significant global health issue, with rising prevalence and growing disparities across...
22/05/2026

Male infertility is emerging as a significant global health issue, with rising prevalence and growing disparities across regions.
An analysis in the Chinese Medical Journal, spanning 1990 to 2021, shows increasing burden driven by population dynamics and projects further growth. The findings underscore the importance of strengthening reproductive healthcare and targeted screening efforts.

Read more:
https://journals.lww.com/cmj/fulltext/9900/global_burden_of_male_infertility_from_1990_to.1958.aspx

A global study in the Chinese Medical Journal reveals that ischemic heart disease cases have increased significantly sin...
21/05/2026

A global study in the Chinese Medical Journal reveals that ischemic heart disease cases have increased significantly since 1990, although age-standardized incidence, mortality, and disability-adjusted life years have declined.
Future projections indicate continued reductions through 2030, with regional disparities persisting, especially in low- and middle-income settings.

Read more:
https://journals.lww.com/cmj/fulltext/9900/global_burden_of_ischemic_heart_disease_from_1990.1966.aspx

What drives intestinal ischemia/reperfusion injury?A study in the Chinese Medical Journal identifies GADD45B as a key re...
19/05/2026

What drives intestinal ischemia/reperfusion injury?

A study in the Chinese Medical Journal identifies GADD45B as a key regulator that worsens injury by promoting apoptosis and intestinal barrier damage. Mechanistically, it drives DNA demethylation and activates the Hippo pathway via the TET1/MST1 axis.
Targeting this pathway could open new therapeutic possibilities.

Read more: https://journals.lww.com/cmj/fulltext/9900/gadd45b_promotes_apoptosis_in_intestinal.2014.aspx

How safe is immunotherapy in older patients?A study published in the Chinese Medical Journal shows that elderly lung can...
18/05/2026

How safe is immunotherapy in older patients?

A study published in the Chinese Medical Journal shows that elderly lung cancer patients experience higher rates of immune-related side effects compared to those with gastrointestinal cancers.

Interestingly, side effects differ; skin toxicity is more common in GI cancers, while thyroid issues are more frequent in lung cancer.

Read more:
https://journals.lww.com/cmj/fulltext/9900/immune_related_adverse_events_between_elderly.2011.aspx

Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal dn fetal complications. A study published in t...
15/05/2026

Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal dn fetal complications.

A study published in the Chinese Medical Journal evaluated the association between grip strength and HDP risk. Findings suggest that lower grip strength in early pregnancy is associated with higher risk of developing these conditions, with relative grip strength showing a clear inverse relationship.
The results of this study highlight the potential of grip strength as a simple, non-invasive tool for early risk stratification.

Read more: https://journals.lww.com/cmj/fulltext/9900/association_between_grip_strength_and_hypertensive.2007.aspx

Effective management of liver disease is critical to improving patient outcomes. A study published in the Chinese Medica...
13/05/2026

Effective management of liver disease is critical to improving patient outcomes.

A study published in the Chinese Medical Journal evaluated the clinical characteristics, treatment approaches, and outcomes in patients with liver disease. The study reveals how disease severity, comorbidities, and management strategies influence prognosis and survival.

Strategic care pathways and early interventions are essential for reducing complications and improving long-term outcomes in this high-risk population.

Read more: https://journals.lww.com/cmj/fulltext/9900/management_and_outcomes_of_patients_with_liver.2004.aspx

Sepsis involves dysregulated immune responses that can drive excessive inflammation.A Chinese Medical Journal study show...
12/05/2026

Sepsis involves dysregulated immune responses that can drive excessive inflammation.

A Chinese Medical Journal study shows reticulocalbin 3 enhances monocyte-to-macrophage differentiation by modulating autophagy, contributing to immune activation. These findings highlight a potential target for improving sepsis treatment strategies.

Read more: https://journals.lww.com/cmj/fulltext/9900/effect_of_reticulocalbin_3_on.1994.aspx

Clinical decision making relies heavily on accurately assessing disease severity. A review published in the Chinese Medi...
12/05/2026

Clinical decision making relies heavily on accurately assessing disease severity.

A review published in the Chinese Medical Journal explores approaches to classify disease burden into minimal, moderate, and marked categories. Such stratification ensures consistency in clinical evaluation, supporting better monitoring of disease progression, and enhances treatment assessment.
Standardized severity grading can also strengthen research comparability and guide better targeted strategies.

Read more: https://journals.lww.com/cmj/fulltext/9900/estimating_minimal,_moderate,_and_marked.1999.aspx

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