Nightingale Project - Johannes Gutenberg University Mainz

Nightingale Project - Johannes Gutenberg University Mainz Check out our demos on our website and learn more about cardiovascular health and how to preserve it

17/06/2025

We are working on an applied research project around a crucial issue: the automatic prediction of information about war injuries from 3D scans of the human body. Matthieu Brossard Camille Aubry Jay Asodariya Pierre Clément

The project :

Thanks to 3D imaging of the human body, we can now visualize injuries from all angles. But there is still a lot of work to do to automatically identify the characteristics of the injured areas from these 3D models. It’s a challenge that is still little explored.

Our first objective: automatically segment wounds from 3D files in Wavefront format (.obj, .mtl, .png), to facilitate medical analysis.

The goal

- Accelerate medical evaluation of injuries in urgent contexts.
- Provide a diagnostic aid tool based on artificial intelligence.
- Provide an interactive demo of the project, accessible via the web.

How does it work?
We set up a method based on 2D projections of the 3D model:

- The model is projected from different angles to create 2D views.
- These views are analyzed by DeepSkin (https://github.com/Nico-Curti/Deepskin), a neural network specialized in wound segmentation.
- The results are reprojected in 3D to mark the injured areas.

An interactive web interface has been developed to test this approach:

- The user uploads a 3D model from their computer or chooses a pre-loaded one.
- They can visualize and compare the original model and the segmented model directly in the browser.

This project shows that a bridge is possible between medicine, AI, and 3D visualization. We will continue to improve it, with a more intuitive interface and finer segmentation.

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12/06/2025

Gender Inequality in Cardiovascular Disease: A Too Often Overlooked Issue

Cardiovascular diseases are the leading cause of death among women worldwide, ahead of breast cancer. Yet, they remain under-recognized, underdiagnosed, and undertreated in women compared to men.

Some telling facts:

- Symptoms in women are often less typical (fatigue, nausea, shortness of breath), which can delay diagnosis.
- Women are less frequently referred for specialized exams or appropriate treatments.
- Clinical studies have long been focused on male populations, ignoring biological and hormonal differences specific to women.

And this issue extends beyond cardiovascular diseases:

Chronic conditions such as diabetes, autoimmune disorders, and chronic pain affect women more frequently, but are often taken less seriously in healthcare settings.

Why is this a public health issue?

Because truly effective medicine must be inclusive and personalized. Understanding biological, social, and behavioral differences between sexes is essential to improve prevention, diagnosis, and care.

It's time to:

- Include more women in clinical trials
- Tailor prevention campaigns to women's specific realities

Taking care of your health — whether you're a woman or a man — is essential.

Differences exist, but prevention matters for everyone.
To better understand your risk factors and explore interactive, AI-powered tools, check out the demos on our Nightingale platform: https://nightingale.uni-mainz.de/ #/

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10/06/2025

How AI Is Changing the Game in Cardiovascular Disease Prevention

Every year, 18 million people die from cardiovascular diseases worldwide, according to the WHO. Yet many of these deaths could be prevented with better prevention, earlier diagnosis, and more informed decision-making.

That’s where artificial intelligence comes in — and innovative projects like Nightingale, developed by the University of Mainz, are already showing tremendous potential

HealthLife: An interactive AI-powered questionnaire that analyzes your lifestyle habits (sleep, nutrition, physical activity, etc.) to assess your cardiovascular risk.

HealthView: A tool using neural networks to automatically detect cardiac
abnormalities in X-rays, with clear explanations to help interpret the results.

HealthMap: A global health data visualization platform to compare cardiovascular risk factors across countries and regions.

Here’s how AI truly changes the game:

- AI no longer just predicts — it explains.
- It helps visualize complex data in an intuitive way.
- It works upstream, identifying risks before symptoms even appear — saving lives.

Try the demos here: https://nightingale.uni-mainz.de/ #/

We had the pleasure of welcoming three talented interns: Aurora, Tommi, and Leo! They are currently studying Industrial ...
05/06/2025

We had the pleasure of welcoming three talented interns: Aurora, Tommi, and Leo!

They are currently studying Industrial Management and Engineering at Metropolia University of Applied Sciences, with a major in Business Management in the ICT sector. During their 10-week internship, they took on an exciting challenge: creating a video game based on a historical and human-centered theme.

The competition "QSI Skills Challenge 2025" took place over three weeks, from April 23 to May 9, and they participated during their free time—on top of their internship responsibilities.
The result? “A Light in the Dark”, an immersive game that puts players in the shoes of a fictional nurse and close friend of Florence Nightingale during the Crimean War (1853–1856).

In this game, players face the challenges of war, care for wounded and sick soldiers, and discover the history of medicine and the role of women in the field. It’s a thoughtful blend of storytelling, education, and current relevance.

We are proud to share that they won the competition thanks to their creativity and dedication!

What did this experience bring you, and what are your plans for the future?
The main goal was to gain experience with different types of projects.
We also wanted to learn more about sustainability and challenge ourselves to do something we had never done before.

Play the game here:
https://play.unity.com/en/games/4d152102-062f-42a9-adda-a6af394a7a9e/a-light-in-the-dark

Watch the team's video presentation of the game:
https://m.youtube.com/watch?v=XyfqI39H76Y&t=5s

Huge congratulations to our interns for this amazing achievement and their outstanding commitment!

Aurora Jokela Tommi K.

03/06/2025

Workplace Stress: A Real Risk Factor for Cardiovascular Health

Work-related stress is not just a source of discomfort or fatigue — it's also a major risk factor for cardiovascular diseases.

When stress becomes chronic, it leads to a sustained increase in hormones like cortisol and adrenaline, which raise heart rate and blood pressure. This constant strain can damage blood vessels and promote the development of hypertension, heart attacks, or strokes.

Additionally, professional stress often leads to risky behaviors such as smoking, poor diet, and lack of physical activity — all of which worsen cardiovascular health.

It is therefore essential for both companies and employees to implement concrete actions to reduce workplace stress:

- Improve working conditions
- Promote a healthy work-life balance
- Offer relaxation spaces and well-being activities

Workplace health also means preventing long-term risks that can be costly for both employees and organizations.

Let’s take care of our hearts — even at the office!

The Nightingale project at the University of Mainz uses innovative technologies to better understand the impact of professional stress on cardiovascular health. This promising research paves the way for practical solutions to help prevent work-related health risks. Click the link to learn more: https://nightingale.uni-mainz.de/ #/

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30/05/2025

Climate and chronic disease : a link invisible, but real

Climate change is not only an environmental crisis, it is also a global health crisis. It has a direct impact on our health, particularly on chronic diseases such as cardiovascular diseases, diabetes, asthma, and mental health.

How does the climate worsen these diseases?

- Extreme heat : increase the risk at infraction, AVC and the dehydration
- Pollution of the air : favorised the diseases respiratory and the cardiovascular
- Insecurity food : disruption climate = less quality food = risk for the diabetes and hypertension
- Propagation at diseases : Mosquitoes move and spread chronic infections.
- Mental health : stress climate, anxiety ecological, isolation

What to do ?

Act for the climate, is protect our health, therefore :

- Go to the less poluante emission,
- More the space green
- To have one alimentation more durable
- To have a city with to have cities better adapted to the coming changes.

To better preserve your health and assess the situation, make an appointment on our site. This tool is for your information and to help you better understand your situation, but in case of doubt or symptoms, do not hesitate to consult a health professional. Click on the link below: https://nightingale.uni-mainz.de/

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27/05/2025

Actually, sleep can influence cardiovascular disease.

A study by Dr. Jean-Philippe Empana showed that five components of sleep are linked to cardiovascular disease. These five components are: sleep duration per night, chronotype (the time of day when we are naturally more awake or more tired), frequency of insomnia, excessive daytime sleepiness, and sleep apnea.
Sleep has a strong impact on health and well-being. It is associated with the deterioration of health, including mood disorders, depression, weight gain, infections, diabetes, and hypertension – all of which are directly linked to cardiovascular disease.

How can sleep play a role in cardiovascular disease?

Short sleep duration is associated with an increased risk. Sleeping 5 hours or less per night increases the risk of hypertension by 60% in middle-aged adults.
Quality sleep allows the heart to rest and recover, thereby reducing the risk of cardiovascular disease.

How much sleep do you really need?

Sleeping less than 5 hours or more than 9 hours per night should be avoided. The ideal sleep duration is between 7 and 9 hours of good-quality sleep, combined with healthy eating and regular physical activity in order to maintain a healthy lifestyle.
If you still have questions or concerns, we suggest you visit our website and learn more about your situation using our artificial intelligence models. Follow this link to access it: https://nightingale.uni-mainz.de/ #/

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22/05/2025

Cardiovascular disease is the leading cause of death worldwide.

Often silent, it progresses quietly until it’s sometimes too late. However, in many cases, it can be prevented through simple daily actions: eating better, moving more, sleeping well, and seeing a doctor regularly.

To better understand the risks — and above all, to help people take action — the World Heart Map was created. This clear, interactive, and accessible tool shows the state of heart health around the world and raises awareness of the challenges we face.

The World Heart Map is based on data from the Gutenberg Health Study, a leading study in Europe. Thanks to artificial intelligence, it evaluated cardiovascular risk in more than 200 countries, taking into account factors such as to***co use, alcohol consumption, BMI, physical activity, stress, sleep, education level, and access to healthcare.

Cardiovascular diseases (like heart attacks, strokes, and high blood pressure) cause about 18 million deaths each year, more than one-third of all global deaths :

- However, many of these can be prevented thanks to:
- Better lifestyle habits
- Regular health check-ups
- Quitting smoking
- Reducing stress

The World Heart Map helps people better understand their risks, identifies the most affected areas, and strengthens global prevention efforts.
Click the link to access the map : https://worldheartmap.nightingale.uni-mainz.de

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20/05/2025

Aging is considered a major risk factor for chronic diseases.

The aging of the population has led to a significant increase in the incidence of chronic illnesses among the elderly, particularly heart-related conditions.

Recent studies have shown that elderly aged between 60 and 90 become more fragile when they have health problems related to the heart and blood vessels, such as hypertension, high cholesterol, and others) (according to AppoloHospital)

Aging can cause changes in the heart and blood vessels. As we age, the heart may no longer beat as quickly during physical effort or stressful situations. However, when aging, the heart rate in a resting state (number of beats per minute) does not change significantly. Over time, fatty deposits can build up in the artery walls, which can become a major cause of chronic heart disease.

Because of the baby boom, the number of seniors over 65 continues to grow worldwide. This also means more people with illnesses and in need of care, which could overwhelm hospitals and retirement homes. It is essential to think about your heart health today, to make it better for tomorrow. Take care of yourself now by monitoring your health, especially your heart. To support you, visit our website at : https://nightingale.uni-mainz.de/ #/

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15/05/2025

Test your knowledge with Lifesaver

Here is Lifesaver, a model developed by the Nightingale project with the purpose of teaching through a questionnaire. Find out more about your heart and body, as well as the right methods to save lives!

You can test your knowledge or even learn how to perform CPR (Cardiopulmonary Resuscitation) and how to use an AED (Automatic External Defibrillator). However, we advise you to practice CPR with qualified personnel, as badly performed CPR could cause damage to the victim’s body or just not be efficient at all.

Without further ado, we recommend you to try it by following this link: https://nightingale.uni-mainz.de/ #/

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