اوراسكوب - OraScope

اوراسكوب - OraScope OraScope is a specialized lab in the diagnosis of Oral & Maxillofacial diseases and tumors.

اوراسكوب هو معمل متخصص في تشخيص أمراض وأورام الفم والوجه والفكين.

OraScope is an Oral and Maxillofacial Pathology Lab specializing in the diagnosis of diseases and conditions affecting the oral cavity, jaws, and related structures. Our team includes specialists with clinical and academic expertise, ensuring that each case is reviewed carefully and thoroughly. We aim to provide accurate and timely diagnostic reports to support treatment planning and patient care.

Our Services Include:
• Biopsy examination and histopathological diagnosis
• Fine needle aspiration cytology (FNAC)
• Slide consultation and second opinions
• Histomorphometric image analysis and statistical interpretation for research purposes



أوراسكوب هو معمل أمراض الفم والوجه والفكين متخصص في تشخيص الأمراض والحالات التي تصيب الفم، والفكين، والهياكل المرتبطة بهما

يضم فريقنا مختصين ذوي خبرة اكلينيكية وأكاديمية، مما يضمن مراجعة كل حالة بعناية ودقة. نهدف إلى تقديم تقارير تشخيصية دقيقة وسريعه لدعم تخطيط العلاج ورعاية المرضى.

:تشمل خدماتنا
فحص الأنسجه والتشخيص النسيجي المرضي •
سحب الخلايا بالإبرة الدقيقة •
مراجعة الشرائح وتقديم الآراء الثانية •
التحليل الصوري الكمي للنسيج والتفسير الإحصائي للأبحاث•

Lately, we have encountered some cases of orthokeratinized odontogenic cyst (OOC) that presented as surprisingly large l...
17/08/2026

Lately, we have encountered some cases of orthokeratinized odontogenic cyst (OOC) that presented as surprisingly large lesions, with marked expansion and a clinically aggressive appearance.

Although OOC is generally considered an indolent odontogenic cyst with a favorable prognosis, larger lesions may occasionally show extensive expansion and multilocularity, creating a diagnostic challenge.

This highlights an important diagnostic pitfall: a large, expansile lesion with keratinized epithelium should not automatically be classified as an odontogenic keratocyst (OKC).

OOC is characterized by a mature orthokeratinized lining with a prominent granular cell layer, whereas OKC typically shows a parakeratinized, corrugated lining with palisaded basal cells. However, secondary inflammation or other epithelial changes may obscure these characteristic features and create areas of histologic overlap.

Careful evaluation of the entire epithelial lining, adequate sampling, and correlation with the clinical and radiographic findings are essential for an accurate diagnosis.

Let’s take a moment to appreciate this interesting case we encountered in our lab of ameloblastoma demonstrating granula...
02/08/2026

Let’s take a moment to appreciate this interesting case we encountered in our lab of ameloblastoma demonstrating granular cell changes.

The case involved a 23-year-old female presenting with a lesion in the lower anterior mandible. Radiographically, it appeared as a well-defined multilocular radiolucency with cortical expansion.

Granular cell change is an uncommon histopathologic feature of ameloblastoma resulting from the accumulation of lysosomes within the cytoplasm of the tumor cells.

Although rare, recognizing this pattern is important for accurate diagnosis and to avoid confusion with other granular cell lesions of the jaws. In this case, cystic degeneration was also identified, highlighting the diverse histopathologic spectrum of ameloblastoma.

Courtesy of Dr. Abdallah Gaber

عدى سنه على بداية معمل أوراسكوب، وكان لازم نحتفل مع الناس اللي كانوا جزء من الرحلة😍يوم جميل مع أصحابنا وزمايلنا من الأطب...
26/07/2026

عدى سنه على بداية معمل أوراسكوب، وكان لازم نحتفل مع الناس اللي كانوا جزء من الرحلة😍

يوم جميل مع أصحابنا وزمايلنا من الأطباء والجراحين، وضحك ولمة حلوة بعيد عن الشغل.

وطبعًا افتقدنا كل اللي مقدروش يكونوا معانا، وإن شاء الله نجتمع كلنا في أقرب مناسبة.

شكرًا لكل اللي دعمنا ووثق فينا. وشكر خاص لـ Vega Lab على دعمهم وتعاونهم المستمر، إن شاء الله اللي جاي يكون أكبر وأحسن، ونفضل دايمًا عند حسن ظنكم🤍

🎉 Happy 1st Anniversary…OraScope 🎉

Mohamed Osama Sara Badawy Nora Mohamed Kamal Hadeel Kotat

An interesting case of osteoblastoma in a 26-year-old male presenting with a swelling involving the upper right anterior...
04/07/2026

An interesting case of osteoblastoma in a 26-year-old male presenting with a swelling involving the upper right anterior maxilla.
Radiographically, the lesion appeared as a well-defined multilocular radiolucency with cortical expansion and focal perforation.

Histopathologic examination revealed a highly cellular bone-forming lesion composed of interlacing trabeculae of osteoid and woven bone lined by prominent plump osteoblasts within a vascular fibrocellular stroma. Numerous multinucleated giant cells and blood-filled cystic spaces consistent with secondary aneurysmal bone cyst (ABC)-like changes were also identified.

Osteoblastoma is a rare benign bone-forming tumor that is uncommon in the jaws. Secondary ABC-like changes may contribute to rapid expansion and can complicate both the radiographic and histologic appearance.

Careful clinicoradiologic and histopathologic correlation is essential to distinguish it from other bone-forming lesions, particularly low-grade osteosarcoma, as treatment and prognosis differ significantly. Histopathologic differentiation relies on the absence of infiltrative growth, significant cytologic atypia, and atypical mitotic figures.

Courtesy of Dr Abdallah Gaber

حالة من مرض الزهري (Syphilis) بتأكد إن التشخيص مش تحليل وبس. رغم إن التحليل المبدأي كان سلبي، إلا إن الصورة الإكلينيكية ...
13/06/2026

حالة من مرض الزهري (Syphilis) بتأكد إن التشخيص مش تحليل وبس. رغم إن التحليل المبدأي كان سلبي، إلا إن الصورة الإكلينيكية والباثولوجية خلتنا نتمسك بالتشخيص ونطلب فحوصات أدق، والنتيجة طلعت إيجابية.

الأهم إن التشخيص هنا ما أنقذش المريض بس، لكنه كان مهم كمان لحماية الزوجه الحامل وجنينها. ‎

مش كل نتيجة سلبية بتنفي المرض، وأحيانًا قراءة الصورة كاملة وعدم تجاهل التفاصيل هو اللي بيقود للتشخيص الصحيح!

A 32-year-old male presented with multiple oral lesions involving the labial mucosa, buccal mucosa, palate and tongue.

Histopathologic findings, when correlated with the clinical presentation, were highly suggestive of secondary syphilis, including features consistent with snail-track ulcers, condyloma lata and mucous patches. However, as the histopathologic features of syphilis are often nonspecific, clinicopathologic correlation was essential in raising suspicion for the diagnosis.

Interestingly, the initial VDRL screening test was negative, despite the patient's pregnant wife testing positive for syphilis. Given the strong clinical and histologic suspicion, further treponemal-specific testing was recommended and subsequently returned positive, confirming the diagnosis.

This case highlights the importance of not relying solely on screening tests. When clinical and microscopic findings strongly suggest syphilis, additional confirmatory testing may be warranted, as false-negative tests can occasionally occur.

Courtesy of Dr. Mahmoud El-Rayes

🔬 Tip #5 Multiple Incisional Biopsies in Large Lesions...Large oral lesions are often heterogeneous. Different areas ma...
02/06/2026

🔬 Tip #5

Multiple Incisional Biopsies in Large Lesions...

Large oral lesions are often heterogeneous. Different areas may exhibit different histopathological features, especially when red, white, ulcerated, indurated, or exophytic components coexist.

Obtaining multiple biopsies from clinically distinct areas improves diagnostic accuracy, reduces sampling error, and supports appropriate treatment planning.

Remember: Biopsy the most informative areas, not just the most accessible ones!!

A 40-year-old male presented with a destructive right maxillary lesion extending into and obliterating the maxillary sin...
17/05/2026

A 40-year-old male presented with a destructive right maxillary lesion extending into and obliterating the maxillary sinus.

Under the microscope, H&E sections revealed extensive tissue necrosis with fungal hyphae deeply infiltrating the tissue and invading blood vessels, with associated thrombosis, classic features of an ANGIOINVASIVE FUNGAL INFECTION. Areas of necrotic bone and acute inflammatory infiltrate were also identified.

The fungal hyphae appeared broad, ribbon-like, predominantly non-septate, with irregular branching, features that strongly raise suspicion for MUCORMYCOSIS.

However, as we mention in our pathology report, while histopathology can strongly suggest the diagnosis, definitive species identification ultimately requires microbiological culture correlation.

‎‏⚠️ Oral Lichen Planus is a chronic inflammatory oral condition classified as an oral potentially malignant disorder.‎‏...
05/05/2026

‎‏⚠️ Oral Lichen Planus is a chronic inflammatory oral condition classified as an oral potentially malignant disorder.

‎‏Biopsy is important to confirm diagnosis and rule out dysplasia or malignancy.

‎‏Long-term follow-up is essential, especially if there are warning changes like ulceration, induration, persistent red or mixed lesions, or symptom progression.

‎‏Early detection and monitoring are key!

‎الحزاز المسطح الفموي هو حالة التهابية مزمنة تُصنَّف ضمن الاضطرابات الفموية ذات الخطورة المحتملة للتحول السرطاني

‎ لتأكيد التشخيص أخذ عينه خطوه مهمه وذلك ايضا لاستبعاد وجود خلل تنسجي أو تغيرات سرطانية

‎المتابعة طويلة المدى ضرورية خصوصًا عند ظهور علامات مثل التقرحات، التصلب، أو البقع الحمراء/المختلطة، أو تدهور الأعراض

‎الكشف المبكر والمتابعة المنتظمة أساسيان لسلامة المريض!

A 28-year-old female presented with a painless gingival swelling in the anterior region of one-year duration.Histopathol...
16/04/2026

A 28-year-old female presented with a painless gingival swelling in the anterior region of one-year duration.

Histopathological examination confirmed Giant Cell Fibroma, characterized by giant, stellate and multinucleated fibroblasts, predominantly located in the superficial connective tissue beneath the epithelium.

Interestingly, this lesion can exhibit a papillary surface architecture, as shown in our case, which may lead to clinical confusion with other papillary lesions.

Giant Cell Fibroma is a benign fibrous lesion that most commonly affects the gingiva. Although it is usually small, larger presentations can occur with variable clinical appearance. Simple surgical excision is curative, with rare recurrence.

Courtesy of Dr. Mahmoud El-Rayes

A 15-year-old female presented with a unilocular radiolucent lesion associated with the permanent right second molar. Hi...
04/04/2026

A 15-year-old female presented with a unilocular radiolucent lesion associated with the permanent right second molar.

Histopathological examination showed a cystic cavity lined by ameloblastomatous epithelium, with epithelial islands infiltrating the fibrous wall—consistent with mural unicystic ameloblastoma.

As outlined in the WHO 2022 classification, this subtype exhibits a more aggressive biological behavior compared to luminal and intraluminal variants, owing to true mural invasion. Therefore, current evidence supports managing mural lesions with a more radical surgical approach, similar to conventional ameloblastoma, rather than relying on conservative enucleation alone.

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٥ ش عز الدين محمد عطيه/النزهه الجديده
Cairo

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Wednesday 2pm - 9pm
Thursday 2pm - 9pm
Saturday 2pm - 9pm
Sunday 2pm - 9pm

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