Intensive Care Medicine

Intensive Care Medicine The official page for ICM, Intensive Care Medicine.

ICM is an international peer-reviewed medical journal intended for all those who are involved in intensive care medicine. ''Intensive Care Medicine'' is the publication platform for the communication and exchange of current work and ideas in intensive care medicine. The journal publishes original research papers, reviews, as well as discussions on technology, methods, new apparatus and modificatio

ns of standard techniques and correspondence concerning matters of topical interest or relating to published material. Official journal of The European Society of Intensive Care Medicine and The European Society of Paediatric and Neonatal Intensive Care.
12 issues per year.

https://zurl.co/44Jb5 Early full nutritional replacement may cause harm during acute critical illness through overfeedin...
11/06/2026

https://zurl.co/44Jb5 Early full nutritional replacement may cause harm during acute critical illness through overfeeding, refeeding syndrome, impaired autophagy and metabolic intolerance. Low-calorie and low-protein strategies may improve recovery and reduce complications. In recovery, priorities shift towards lean body mass restoration and functional recovery. Evidence defining optimal macronutrient targets remains limited.

https://zurl.co/r4ocQ ARDS mimickers may meet ARDS criteria without an identifiable classical risk factor and represent ...
11/06/2026

https://zurl.co/r4ocQ ARDS mimickers may meet ARDS criteria without an identifiable classical risk factor and represent about 8% of ARDS cases. Etiologies are classically categorised into immune-mediated, drug-induced, neoplastic and idiopathic disorders. Medical history, physical examination, autoimmune testing, chest CT and bronchoalveolar lavage support a standardised diagnostic work-up. Several patterns can inform the diagnosis, but they are not disease-specific.

https://zurl.co/78hCF The MICROINHALO trial included 250 critically ill intubated patients across 10 ICUs in Italy and I...
10/06/2026

https://zurl.co/78hCF The MICROINHALO trial included 250 critically ill intubated patients across 10 ICUs in Italy and Israel. Automatic management did not significantly reduce Day 3 bacterial tracheobronchial colonization compared with manual management. Clinically diagnosed and microbiologically confirmed VAP rates were lower with automatic management. It also showed fewer cuff-pressure values outside the safety range and a higher daily subglottic secretion drainage volume.

https://zurl.co/M0mAX The field of patient–ventilator asynchronies still lacks consensus on terminology and classificati...
10/06/2026

https://zurl.co/M0mAX The field of patient–ventilator asynchronies still lacks consensus on terminology and classification. A mechanism-based framework may offer physiological insight, while phase-based approaches remain intuitive and applicable at the bedside. The SYNAPsE study provides a structured expert synthesis and a practical framework.

https://zurl.co/EVYam A multinational ICU cohort included 845 adults with microbiologically confirmed bacterial infectio...
09/06/2026

https://zurl.co/EVYam A multinational ICU cohort included 845 adults with microbiologically confirmed bacterial infections who received empirical antimicrobials. Appropriate therapy was given to 87.7% of patients and was associated with lower ICU mortality, more antimicrobial-free days and more mechanical ventilation-free days. The survival benefit was consistent across diagnostic certainty and most pronounced at SOFA scores of 3 to 9.

https://zurl.co/ANFli -Quizz A 17-year-old male with no past medical history presented with acute respiratory failure...
09/06/2026

https://zurl.co/ANFli -Quizz A 17-year-old male with no past medical history presented with acute respiratory failure due to viral pneumonia. Initial CT showed right lower lobe consolidation, small pneumomediastinum and subcutaneous emphysema. Within 48 hours, worsening subcutaneous emphysema, pneumothorax and pneumomediastinum led to VV-ECMO support, with the Macklin effect explaining air tracking along bronchovascular bundles.

-Quizz A 17-year-old male with no past medical history presents with acute respiratory failure due to viral pneumonia...
08/06/2026

-Quizz A 17-year-old male with no past medical history presents with acute respiratory failure due to viral pneumonia. On ICU admission, CT shows right lower lobe consolidation, small pneumomediastinum and subcutaneous emphysema. Within 48 hours, despite mechanical ventilation, he develops worsening subcutaneous emphysema, pneumothorax and pneumomediastinum, requiring VV-ECMO. What is the most likely mechanism explaining these findings?

https://zurl.co/fQimy Critical illness affects patients, families and ICU staff as a shared social and emotional event. ...
08/06/2026

https://zurl.co/fQimy Critical illness affects patients, families and ICU staff as a shared social and emotional event. About a third of relatives develop symptoms of PTSD. Family-centred care, burnout prevention, ethical climate, dedicated relational time and staff encouragement are presented as core ICU priorities.

https://zurl.co/V9zBt AKI and fluid balance disorders are common before and during ECMO, and around half of cases receiv...
07/06/2026

https://zurl.co/V9zBt AKI and fluid balance disorders are common before and during ECMO, and around half of cases receive CRRT. The 36th ADQI meeting developed multidisciplinary international expert recommendations across five working groups. Priorities included AKI risk, fluid management, indications for CRRT, CRRT delivery during ECMO, biomarkers, blood purification and drug dosing. Knowledge gaps and research priorities were identified.

https://zurl.co/OW3Yk Non-invasive ICP tools cannot reproduce invasive catheter monitoring or provide exact pressure val...
07/06/2026

https://zurl.co/OW3Yk Non-invasive ICP tools cannot reproduce invasive catheter monitoring or provide exact pressure values. Their role may lie in supporting dynamic assessment of the injured brain through indirect indicators of tolerance to ICP burden. Multimodal non-invasive monitoring may help detect deterioration, reduced compensatory reserve, impaired adaptation, harmful trajectories and early decompensation while informing escalation strategies.

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