19/07/2026
HEATWAVE & MENTAL HEALTH MEDICATIONS: What You Need to Know
Some mental health medications can make it harder for your body to cope with extreme heat. This isn’t talked about enough — but it’s important, especially during a heatwave.
These medications can affect sweating, hydration, temperature regulation, or sun sensitivity. That means your body may struggle more to stay cool.
Medications that may increase heat sensitivity (not a complete list, check your medication leaflets, any doubt, call your chemist)
1. Antipsychotics
Certain antipsychotics can reduce your ability to sweat or regulate temperature.
Common examples include:
Olanzapine
Risperidone
Quetiapine
Clozapine
Haloperidol
These can increase the risk of overheating or dehydration.
2. Antidepressants
Some antidepressants can affect sweating, hydration, or sun sensitivity.
This can include:
SSRIs (e.g., sertraline, fluoxetine, citalopram)
SNRIs (e.g., venlafaxine, duloxetine)
Tricyclics (e.g., amitriptyline, imipramine) — these are particularly known for heat‑related sensitivity
MAOIs
3. Mood Stabilisers
Some mood stabilisers can impact hydration or salt balance.
Examples include:
Lithium (heat + dehydration can affect lithium levels)
Valproate
Carbamazepine
4. Anti‑Anxiety Medications
Sedating medications can make you less aware of heat stress.
Examples include:
Benzodiazepines (e.g., diazepam, lorazepam)
Pregabalin
Gabapentin
5. ADHD / Stimulant Medications
Stimulants can increase body temperature and reduce appetite or thirst.
Examples include:
Methylphenidate
Lisdexamfetamine
Dexamfetamine
6. Medications that increase sun sensitivity
Some mental health medications can make skin more reactive to sunlight.
Examples include:
Certain antidepressants (especially tricyclics)
Some antipsychotics
Mood stabilisers like lamotrigine
www.livelifenotstrife.co.uk