PluchinoLab - Regenerative Neuroimmunology

PluchinoLab - Regenerative Neuroimmunology A group of young, curious and enthusiastic experimentalists dreaming to repair the injured brain. We We practice the principle of think FAST, work FASTER!!

Happy world MS day 🧡🧡🧡
30/05/2026

Happy world MS day 🧡🧡🧡

Share stories, raise awareness and campaign with everyone affected by multiple sclerosis (MS). The theme for 2024-2026 is diagnosis, support the My MS Diagnosis campaign today. World MS Day is coordinated by the MS International Federation and its members.

I am deeply honoured and humbled to share that I have been elected as a Fellow of the Academy of Medical Sciences (FMedS...
21/05/2026

I am deeply honoured and humbled to share that I have been elected as a Fellow of the Academy of Medical Sciences (FMedSci) — one of the most prestigious recognitions in UK medical science.
This election is a great honour and responsibility. It reflects not just my own work, but the extraordinary dedication of every collaborator, trainee, and patient who has been part of this journey.
Over the past two decades, my team and I have been working at the intersection of stem cell biology, neuroimmunology, and regenerative medicine — pioneering new approaches to understand and treat progressive multiple sclerosis and other neuroinflammatory diseases. From uncovering the key mechanisms of action and signalling underlying neural stem cell-based therapeutics, to defining the emerging field of Regenerative Neuroimmunology, to conducting the first-in-human trial of allogeneic neural stem cells in people with MS, every step has been driven by a single conviction: that science, done boldly and collaboratively, can transform lives.
I join an exceptional cohort of new Fellows from the University of Cambridge — a group whose breadth and brilliance across medical science is truly inspiring — and an esteemed Fellowship of over 1,500 researchers shaping health research and policy in the UK and worldwide.
Looking at the extraordinary colleagues I have the privilege of joining as Fellows, I feel both deeply grateful and genuinely humbled — I can only hope to be worthy of this recognition. As I look ahead, I remain fully dedicated to advancing stem cell technologies for the research and cure of neuroinflammatory diseases — and to fostering inclusive science for early-career researchers — because the future of medicine depends as much on the people we nurture as on the discoveries we make.
Thank you to the Academy, to my mentors, colleagues, and team — past and present — and above all, to the patients who inspire every experiment and every question.
The work continues. 🧠✨

Prestigious research fellowships for Trust clinicians
21/05/2026

Prestigious research fellowships for Trust clinicians

The fellowships recognise outstanding contributions to advancing medical science, including pioneering discovery research and translating innovation into tangible benefits for patients and the wider public.

I am deeply honoured and humbled to share that I have been elected as a Fellow of the Academy of Medical Sciences (FMedS...
21/05/2026

I am deeply honoured and humbled to share that I have been elected as a Fellow of the Academy of Medical Sciences (FMedSci) — one of the most prestigious recognitions in UK medical science.
This election is a great honour and responsibility. It reflects not just my own work, but the extraordinary dedication of every collaborator, trainee, and patient who has been part of this journey.
Over the past two decades, my team and I have been working at the intersection of stem cell biology, neuroimmunology, and regenerative medicine — pioneering new approaches to understand and treat progressive multiple sclerosis and other neuroinflammatory diseases. From uncovering the key mechanisms of action and signalling underlying neural stem cell-based therapeutics, to defining the emerging field of Regenerative Neuroimmunology, to conducting the first-in-human trial of allogeneic neural stem cells in people with MS, every step has been driven by a single conviction: that science, done boldly and collaboratively, can transform lives.
I join an exceptional cohort of new Fellows from the University of Cambridge — a group whose breadth and brilliance across medical science is truly inspiring — and an esteemed Fellowship of over 1,500 researchers shaping health research and policy in the UK and worldwide.
Looking at the extraordinary colleagues I have the privilege of joining as Fellows, I feel both deeply grateful and genuinely humbled — I can only hope to be worthy of this recognition. As I look ahead, I remain fully dedicated to advancing stem cell technologies for the research and cure of neuroinflammatory diseases — and to fostering inclusive science for early-career researchers — because the future of medicine depends as much on the people we nurture as on the discoveries we make.
Thank you to the Academy, to my mentors, colleagues, and team — past and present — and above all, to the patients who inspire every experiment and every question.
The work continues. 🧠✨


___________________________
Sono profondamente onorato e commosso di condividere di essere stato eletto Fellow della Academy of Medical Sciences (FMedSci) — uno dei riconoscimenti più prestigiosi nel campo della scienza medica nel Regno Unito.

Questa elezione rappresenta un grande onore e una grande responsabilità. Riflette non solo il mio lavoro, ma la straordinaria dedizione di ogni collaboratore, tirocinante e paziente che ha fatto parte di questo percorso.

Negli ultimi due decenni, il mio gruppo ed io abbiamo lavorato all'intersezione tra biologia delle cellule staminali, neuroimmunologia e medicina rigenerativa — aprendo nuove strade per comprendere e trattare la sclerosi multipla progressiva e altre malattie neuroinfiammatorie. Dalla scoperta dei principali meccanismi d'azione e di segnalazione alla base delle terapie con cellule staminali neurali, alla definizione del campo emergente della Neuroimmunologia Rigenerativa, fino alla conduzione del primo trial sull'uomo con cellule staminali neurali allogeniche in pazienti con SM — ogni passo è stato guidato da una sola convinzione: che la scienza, praticata con coraggio e in modo collaborativo, può trasformare le vite.

Mi unisco a una straordinaria classe di nuovi Fellows dell'Università di Cambridge — un gruppo la cui ampiezza e brillantezza nel campo della scienza medica è davvero fonte di ispirazione — e a una stimata Fellowship di oltre 1.500 ricercatori che plasmano la ricerca in ambito sanitario e le politiche della salute nel Regno Unito e nel mondo.

Guardando agli straordinari colleghi che ho il privilegio di raggiungere come Fellows, mi sento profondamente grato e sinceramente umile — posso solo sperare di essere degno di questo riconoscimento. Guardando al futuro, rimango pienamente dedicato al progresso delle tecnologie con cellule staminali per la ricerca e la cura delle malattie neuroinfiammatorie — e a promuovere una scienza inclusiva per i ricercatori alle prime armi — perché il futuro della medicina dipende tanto dalle persone che formiamo quanto dalle scoperte che facciamo.

Grazie all'Academy, ai miei mentori, colleghi e al mio team — passati e presenti — e soprattutto ai pazienti che ispirano ogni esperimento e ogni domanda.

Il lavoro continua. 🧠✨


Seven scientists from the fields of biomedical and health research at the University of Cambridge have been elected as Fellows of the Academy of Medical

Had some fantastic time at the last Fusion Conference on Mitochondria & Cell Fate Transitions in beautiful Malta! 🌍 Was ...
13/05/2026

Had some fantastic time at the last Fusion Conference on Mitochondria & Cell Fate Transitions in beautiful Malta! 🌍

Was great to reconnect with so many friends and colleagues, and delighted to have shared our latest data on disease-associated radial glia in progressive MS.

Highly recommended conference! 🧠🔬

Delighted to take part on 20th May, in Pint of Science Cambridge — one of the most joyful and genuinely democratic scien...
13/05/2026

Delighted to take part on 20th May, in Pint of Science Cambridge — one of the most joyful and genuinely democratic science communication festivals in the world.
The idea is beautifully simple: bring leading researchers into your local pub and make science accessible, exciting, and human. No lecture halls. No jargon barriers. Just curiosity, good company, and yes — a pint 🍺.

This year’s Cambridge edition is called “The Beautiful Mind: From Mini-Brains to Mighty Breakthroughs” and the evening will tackle some of the most profound questions in modern neuroscience: How do brains grow? What causes them to break down? And can we repair them? From growing mini-brains in the lab, to uncovering how inflammation drives dementia, to exploring stem cell therapies for multiple sclerosis — the night promises to reveal how cutting-edge science is helping us understand, protect, and even rebuild the human brain. What a lineup of topics 🔬✨.

What makes this extra special is sharing the stage with two exceptionally talented early-career researchers — the brilliant Alex Kingston from Andras Lakatos’s team, and the wonderful Maura Malpetti from our group at Cambridge, who is quite simply a rising star in our field and someone whose work genuinely excites me every time I hear about it 🌟.

As for me — I’ll be exploring one of the most compelling and hopeful questions in modern neurology: Can brain stem cells treat progressive Multiple Sclerosis? Progressive MS remains one of medicine’s most challenging conditions, with devastatingly few effective treatments. I’ll be taking you through the science of neural stem cell therapies — from laboratory discoveries to first-in-human clinical trials — sharing what we’ve learned, what early human studies are beginning to reveal, and where this journey might take us next. It is, at its heart, a story of hope, perseverance, and the future of regenerative neuroimmunology 💙.

📅 Date: 20th May 📍 Venue: Panton Arms, 43 Panton Street, Cambridge CB2 1HL
🎟️ Tickets are ON SALE NOW — and already selling fast!

If you’ve never been to a Pint of Science event, this is your sign. And if you have — you already know why you shouldn’t miss it.

Delighted that the MS Society have renewed core funding for the Cambridge Centre for Myelin Repair for another five year...
13/05/2026

Delighted that the MS Society have renewed core funding for the Cambridge Centre for Myelin Repair for another five years.

Congrats to The University of Edinburgh Centre for MS Research on their successful parallel renewal.

I am truly honoured to serve as co-director of the Centre alongside my esteemed colleagues Prof Ragnhildur Thora Karadottir and Prof Alasdair Coles.

Together, we will focus on the critical questions that follow our first clinical trials: when should myelin repair therapies be used, who will benefit most, and how do age, genetics and disease course shape their success?

By linking biological mechanisms with cutting-edge translational tools — from next-generation human model systems to patient cohorts across the lifespan — we aim to overcome the remaining barriers to effective treatments for progressive MS.

Looking forward to helping find and deliver those treatments to the tens of thousands of people living with MS, together with our local, national, and international partners.

https://www.mssociety.org.uk/research/latest-research/latest-research-news-and-blogs/funding-two-ms-research-centres-renewed

Great science, great friends, great city.Thank you Associazione Italiana Neuroimmunologia (AINI) for the invitation to s...
13/05/2026

Great science, great friends, great city.

Thank you Associazione Italiana Neuroimmunologia (AINI) for the invitation to speak at your 34th Annual Congress in Rome — sharing our work on stem cell technologies for MS with such a wonderful community was a real pleasure!

Delighted that the MS Society have renewed core funding for the Cambridge Centre for Myelin Repair for another five year...
30/04/2026

Delighted that the MS Society have renewed core funding for the Cambridge Centre for Myelin Repair for another five years.

Congrats to The University of Edinburgh Centre for MS Research on their successful parallel renewal.

I am truly honoured to serve as co-director of the Centre alongside my esteemed colleagues Prof Ragnhildur Thora Karadottir and Prof Alasdair Coles.

Together, we will focus on the critical questions that follow our first clinical trials: when should myelin repair therapies be used, who will benefit most, and how do age, genetics and disease course shape their success?

By linking biological mechanisms with cutting-edge translational tools — from next-generation human model systems to patient cohorts across the lifespan — we aim to overcome the remaining barriers to effective treatments for progressive MS.

Looking forward to helping find and deliver those treatments to the tens of thousands of people living with MS, together with our local, national, and international partners.

https://www.mssociety.org.uk/research/latest-research/latest-research-news-and-blogs/funding-two-ms-research-centres-renewed

Our Centres of Excellence in Edinburgh and Cambridge have received new funding to continue their work to find treatments for everyone living with MS.

Address

Wellcome Trust-Medical Research Council Stem Cell Institute University Of Cambridge Clifford; Allbutt Building/Cambridge Biosciences Campus
Cambridge
CB20HA

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