22/04/2026
If you’re considering functional testing, you’ve probably come across names like GI360, DUTCH, Organic Acids (OAT) and SIBO.
These advanced tests can provide insights that routine bloodwork often misses, but how do you know which one is right for you?
This guide breaks down what each test does, who it’s most useful for and how they fit together.
GI360 Stool Test
Best for:
Persistent bloating, IBS, IBD, diarrhoea/constipation, food sensitivities, post-antibiotic gut issues.
What it shows:
Gut microbiome balance, digestive function, inflammation, pathogens (bacteria, parasites, yeast).
Why choose it: Ideal if you want a comprehensive view of gut health and digestion.
DUTCH Complete Hormone Test
Best for:
Perimenopause, menopause, PMS, fatigue, mood changes, sleep issues, HRT monitoring.
What it shows:
Oestrogen, progesterone, testosterone, cortisol rhythm, melatonin, hormone metabolism and neurotransmitter metabolites.
Why choose it:
Perfect for hormone balance questions and understanding how stress affects your health and hormones.
Organic Acids Test (OAT)
Best for:
Fatigue, brain fog, low mood, ADHD/autism support, neurological issues, yeast or bacterial overgrowth.
What it shows:
Energy production pathways, nutrient metabolism, detoxification markers, oxalate levels, neurotransmitter metabolites, microbial by-products.
Why choose it:
Excellent for exploring gut–brain connections and hidden nutrient needs. A good functional lab test for children as it gives a broad overview with just one urine sample.
SIBO Breath Test
Best for:
Daily bloating, excessive gas, IBS symptoms (diarrhoea, constipation, or alternating), poor response to elimination diets.
What it shows: Hydrogen and methane gas patterns produced by bacteria in the small intestine.
Why choose it:
Focused, non-invasive way to check for bacterial overgrowth in the small intestine.
Other Tests to Consider
Kryptopyrrole (Pyroluria) Test:
Can help explain anxiety, addiction issues, mood disorders, poor stress tolerance or focus issues linked to zinc/B6 imbalances.
Food Intolerance Testing:
Highlights IgG food reactions that can contribute to bloating, fatigue, mood or skin issues.
How to Choose the Right Test
Start with your main symptoms: gut, hormones, brain/mood, or metabolism.
Consider whether you need a broad overview (GI360 or OAT) or a focused test (SIBO, DUTCH).
Remember: sometimes a combination of tests gives the clearest picture.
For example:
GI360 + SIBO = full gut overview
DUTCH + OAT = hormones + energy/metabolism
GI360 + Food Sensitivity = digestion + potential triggers