Economics of Population Health Research Centre

07/08/2026

NEW PUBLICATION

Impact of Preventive Treatment on Healthcare Use: A Modeling Study of Statin Treatment

Junwen Zhou, Runguo Wu, Claire Williams, Chris Carvalho, John Robson, Borislava Mihaylova

Value in Health 2026

20/07/2026

NEW PUBLICATION

TaILOR: a randomised trial to compare the clinical and cost-effectiveness of a patient-initiated follow-up (PIFU) strategy compared to standard care pathways in people with inflammatory arthritis: a study protocol

Gretchen Brewer, Victoria Harris, Christopher Mwema, Abhishek Abhishek, Ailsa Bosworth, Christine Bundy, Clare Clark, Elizabeth Conroy, Helen Dakin, Emma Dures, Joe Eddison, Anne Francis, James Galloway, Alice Jennings, Helen Lall, Elizabeth MacPhie, Sam Norton, Mark Perry, Jane Raleigh, Mel Brooke Turfrey & Laura Coates

Trials 2026

Background Inflammatory arthritis comprises lifelong conditions, such as rheumatoid arthritis, axial spondyloarthritis and psoriatic arthritis that require long-term treatment and regular monitoring. People with inflammatory arthritis usually require long-term treatment with immune-suppressing medic...

15/07/2026

NEW PUBLICATION

EPH research published in the BMJ https://doi.org/10.1136/bmj-2026-729694 and Health and Quality of Life Outcomes https://doi.org/10.1186/s12955-025-02457-w demonstrated the importance of long-term safety follow-up of randomised trials. 2 year follow-up of the STAR trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00687-1/fulltext found that robot radiotherapy to the eye reduced the number of injections to the eyes and would be cost-saving. However, extended follow-up showed that the vision of patients who received radiotherapy worsened beyond this initial time period. This safety information would have gone undetected if follow-up had ended at two years, like most trials in this area.

Background The UK STAR trial [Stereotactic Radiotherapy (SRT) for neovascular age-related macular degeneration (nAMD)] compared 16-Gray SRT (n = 274) with double-masked sham SRT (n = 137) in participants with chronic active nAMD. SRT reduced intravitreal anti-vascular endothelial growth fact...

19/06/2026

NEW PAPER

The economic evaluation of the largest and longest clinical trial of its kind has recommended that surgeons should now consider kneecap resurfacing as part of standard care for most patients undergoing total knee replacement

There was no significant difference in primary outcome (OKS) or other clinical endpoints. However, as clinical differences tend to support patellar resurfacing, the resurfacing group had significantly higher QALYs. There was no difference in costs over the 20-year period, and patellar resurfacing ha...

19/06/2026

NEW PAPER

EPH research published in the BMJ this week demonstrated the importance of long-term safety follow-up of randomised trials.

https://doi.org/10.1136/bmj-2026-729694

Two year follow-up of the STAR trial found that robot radiotherapy to the eye reduced the number of injections to the eyes and would be cost-saving.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00687-1/fulltext

However, extended follow-up showed that the vision of patients who received radiotherapy worsened beyond this initial time period. This safety information would have gone undetected if follow-up had ended at two years, like most trials in this area.

Objective To assess the effects of stereotactic radiotherapy (SRT) for neovascular age related macular degeneration (AMD) beyond the two year primary outcome of the StereoTactic radiotherapy for wet Age-Related macular degeneration (STAR) trial. Design Randomised, double masked, sham controlled, dev...

15/06/2026

EPH NEWS

Researchers from EPH participated to the Joint BRCs Health Research Showcase that took place in the Westgate centre, Oxford.

They provided an informal and light-hearted but informative introduction to health economics and its importance by involving members of the public in an interactive quiz.

They also provided a fun interactive game that illustrated the kind of resource prioritisation decisions that health care systems need to make under budget constraints.

10/06/2026

EPH NEWS

Our researchers are at Summer Meeting in Glasgow this week:

- Helen Dakin, Mapping out the territory: Systems thinking for interacting decisions in economic evaluation and health technology assessment. Other co-authors include Fred McElwee, Amanda Adler and Doug Coyle.

- James Altunkaya, Multi-model inference for cost-effectiveness: Addressing structural uncertainties to assess a model averaged value of semaglutide in prediabetes. Other co-authors include Philip Clarke, Amanda Adler and Jose Leal.

Summer 2026: University of GlasgowThe Health Economists’ Study Group Summer 2026 Meeting will be hosted by Health Economics & Health Technology Assessment (HEHTA), University of Glasgow, from 10th-12th June 2026.Registration is now closed. Meeting scheduleThe HESG Summer Meeting will take place at...

09/06/2026

NEW PUBLICATION

The cost and cost-effectiveness of whole-exome and whole-genome sequencing: a systematic literature review

Fred McElwee, Sally Sansom, James Buchanan, Jenny C. Taylor & Sarah Wordsworth

European Journal of Human Genetics (2026)

Existing systematic reviews of the health economic evidence for whole-exome and whole-genome sequencing (WES/WGS) are outdated or restricted to specific diseases or populations. This systematic review aims to provide an update on the health economic evidence for these sequencing options across a bro...

12/05/2026

NEW PUBLICATION

Global income polarization: relative and absolute perspectives

Vanesa Jorda, Miguel Niño-Zarazúa, Laurence (Larry) Roope, Finn Tarp

The Journal of Economic Inequality, 2026

https://rdcu.be/fgfoV

First long-run estimates (1960–2020) of global income polarization, looking beyond inequality to how incomes cluster into groups and how the “middle” evolves.

Oxford Population Health

11/05/2026

EPH NEWS

Dr Liz Morrell presented on "Risk stratification in newly-diagnosed myeloma: Is a sequencing panel a cost-effective option for the NHS?" at the at the British Society for Haematology Annual Scientific Meeting, in Liverpool, 19-21 April.

Other co-authors from EPH are Fred McElwee and prof. Sarah Wordsworth.