19/08/2026
Of 77,356 adults on long-term omeprazole or lansoprazole across 62 English general practices, 62% had no recorded reason for it anywhere in their notes.
Not a weak reason. None at all.
This is rarely carelessness. It is what happens when a medicine is cheap, works well and causes no trouble today. It gets copied from one repeat prescription to the next for a decade and nobody feels they own the decision to stop it.
Two things worth knowing. The safety picture is more reassuring than the headlines suggest: a three-year randomised trial found no rise in fractures, dementia, kidney disease or heart disease. And stopping abruptly after years can produce a rebound in acid, which more than 40% of people get and most read as the original problem returning.
Some people should stay on these medicines, and stopping would be wrong. The question is not whether the drug is helping. It is what it is treating now.
Full essay here.
Of 77,356 English adults on continuous proton pump inhibitor treatment, 62% had no recorded indication anywhere in their notes. Not a weak one. None.