MicroBiome Bank

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MicroBiome Bank MicroBiome Bank, Egészségügyi központ, Budapest elérhetőségei, térképes helyadatai és útbaigazítási információi, kapcsolatfelvételi űrlapja, nyitvatartási ideje, szolgáltatásai, értékelései, fényképei, videói és közleményei.

A C. difficile nem egy egzotikus ország távoli kórokozója: a környezetünkben, a talajban és sok ember bélflórájában is j...
22/06/2026

A C. difficile nem egy egzotikus ország távoli kórokozója: a környezetünkben, a talajban és sok ember bélflórájában is jelen lehet anélkül, hogy bármi problémát okozna. Egészséges, sokszínű bélflóra[G] mellett ez a baktérium csendben megfér a többiek között, mert a „jó" baktériumok (ilyenek nem léteznek, ugye) nem hagynak neki helyet és táplálékot a túlszaporodáshoz. A baj akkor kezdődik, amikor ez az egyensúly felborul.

A leggyakoribb kiváltó ok az antibiotikum-kezelés. Az antibiotikum nemcsak a megcélzott kórokozót pusztítja el vagy csökkenti számában, hanem a védő bélflórát is megritkítja – erről a következő fejezetben részletesen lesz szó. Ebben az új összetételben a C. difficile hirtelen szabad utat kap: elszaporodik, és termelni kezdi azokat a méreganyagokat (toxin A és/vagy B), amelyek a hasmenést és a bélnyálkahártya gyulladását okozzák.

We are a European team working to combat the so-called “hospital infection” caused by *Clostridioides difficile*.Follow ...
21/06/2026

We are a European team working to combat the so-called “hospital infection” caused by *Clostridioides difficile*.

Follow our journey to learn more about this disease, its impact, and the steps being taken to fight it.

This is Chapter 2: a look back at our first three days and the work we've accomplished so far.
Link in the comment section.

❓ Miért tér vissza újra és újra a C. difficile fertőzés?Sokan azt hiszik, hogy a probléma maga a baktérium. Pedig gyakra...
19/06/2026

❓ Miért tér vissza újra és újra a C. difficile fertőzés?

Sokan azt hiszik, hogy a probléma maga a baktérium. Pedig gyakran nem ez a teljes történet. Mi van akkor, ha a valódi gondot nem a fertőzés, hanem a bélben kialakult egyensúlyvesztés okozza?

Az antibiotikumok sokszor megszüntetik a tüneteket, de közben a védelmet nyújtó mikrobiota is sérülhet. Így a C. difficile könnyebben visszatérhet, újra és újra. Ezért fordul elő, hogy egyes betegek hónapokig vagy akár évekig egy ördögi körben ragadnak.

A legújabb megközelítések már nem csak a kórokozóra koncentrálnak, hanem a teljes bélökoszisztéma helyreállítására. Miért történik ez? Hogyan alakul ki? És miért lehet hatékony ott a mikrobiota-transzplantáció, ahol az antibiotikum önmagában nem hoz tartós eredményt?

Erről szól legújabb cikkünk.
👇 Olvasd el a teljes anyagot a kommentben található linken.

Both *Anna Karenina* and *And Quiet Flows the Don* should be considered patient-side intervention tools within the DEMI ...
15/06/2026

Both *Anna Karenina* and *And Quiet Flows the Don* should be considered patient-side intervention tools within the DEMI framework. In a subset of patients with sleep disturbances, they can serve as surprisingly effective therapeutic aids. Their combination of sustained attention, cognitive immersion, and low-stimulation engagement may help facilitate the transition toward sleep, particularly in individuals whose insomnia is driven by rumination, stress, or excessive exposure to digital media.

# # # Medical Implications of Chapter 4 Through the DEMI Framework

**1. Dysbiosis is not a diagnosis but a description of a biological state**

The DEMI framework approaches dysbiosis not as a standalone disease but as a dynamic ecological condition. The first question is therefore always etiological: what factors led to the current state? Potential causes include a low-fiber diet, infections, antibiotic exposure, chronic stress, sleep disruption, inflammatory bowel disease, or long-term medication use. Effective treatment strategies require identifying and addressing these underlying causes rather than focusing solely on the resulting symptoms.

**2. Manifestation must be assessed through both objective and subjective dimensions**

Within the DEMI framework, the same disease may affect different patients in very different ways. For this reason, manifestation is divided into two complementary components. The objective manifestation includes measurable parameters such as stool frequency, stool consistency, meal frequency, food sensitivities, dietary composition, and the extent of dietary restrictions. The subjective manifestation evaluates how much symptoms interfere with daily life, work performance, social functioning, and overall well-being. Together, these dimensions provide a more complete picture of disease burden than either could alone.

**3. Nutrition is the most powerful intervention lever, but not the only one**

The central message of Chapter 4 is that nutrition is one of the strongest modulators of the gut microbiota. Within the DEMI model, dietary habits therefore appear both as etiological factors and as therapeutic tools. Fiber intake, plant diversity, the consumption of ultra-processed foods, and excessive dietary restrictions can all profoundly influence microbial ecosystem function. However, nutrition represents only one component of the broader intervention landscape and should always be evaluated alongside other lifestyle factors that influence microbiota health.

**4. Intervention consists of both patient-driven and physician-driven components**

One of the key strengths of the DEMI framework is its separation of intervention into two distinct domains. The patient-side intervention assesses the extent to which an individual utilizes opportunities under their direct control, including sleep hygiene, regular physical activity, stress management, meditation, adherence to dietary recommendations, and the reduction of harmful habits. The physician-side intervention evaluates the medical tools available to the healthcare team, including structured dietary programs, sleep-cycle interventions, desensitization strategies, pharmacological therapies, and, where appropriate, f***l microbiota transplantation (FMT). Together, these dimensions define the available therapeutic potential.

**5. The intervention score reflects the remaining therapeutic opportunity**

In the DEMI system, the intervention score does not measure disease severity. Instead, it estimates how much of the available therapeutic space has already been utilized by both the patient and the healthcare system. A low intervention score indicates substantial remaining opportunity for meaningful intervention, suggesting that numerous lifestyle and medical strategies are still available. Conversely, a high intervention score implies that many evidence-based options have already been explored, making future improvements more likely to occur incrementally. This perspective helps clinicians and patients develop realistic expectations and better understand the potential impact of future therapeutic decisions.

**In summary, the DEMI model evaluates dysbiosis through three interconnected dimensions: Etiology (what happened), Manifestation (where the patient currently stands), and Intervention (what can still be done). By separating both manifestation and intervention into objective and subjective, as well as patient-side and physician-side components, the framework provides a clinically meaningful assessment of both disease burden and therapeutic potential.**

Link for the 4th chapter is in the comments

As a physician, what I can help you with is dying a little later. That's about it.Today's keywords: ** ** and ** **.To g...
07/06/2026

As a physician, what I can help you with is dying a little later. That's about it.

Today's keywords: ** ** and ** **.

To get there, however, we'll start with a bit of mythology (and I'll also answer the gentleman who asked what FMT has to do with food. We'll come back to that.)

So, I took a look at how many different kinds of food categories I've encountered over the course of my life. Let's see...

There have been foods marketed through a health-focused lens as organic, ecological, functional, health-promoting, preventive, probiotic, prebiotic, immune-supporting, and wellness foods. I've also heard of natural foods, additive-free foods, preservative-free foods, clean-label products, artisanal foods, traditional foods, regional specialties, fitness foods, sustainable foods, ethical foods, carbon-neutral foods, and next-generation foods.

All of these are essentially synonyms for "less sh*tty."

One thing is important: everything depends on quantity and proportion. Water is the foundation of life. If you drink 7–8 liters of it without significant fluid loss, you'll die. So from this point on, we're going to talk about proportions. That's the one word that matters.

How does a particular food relate to your current condition? How does the energy it contains, its chemical compounds, and the microbes associated with it fit your individual situation? Can your body tolerate the amount of antibiotic residues present in a given salami, or can it not?

You know... 8 liters of water.

To make this at least somewhat scientific, we've prepared a guide. In truth, it was written for our patients, but you'll be able to use it as well. Before you begin, though, there's something else I consider important.

Everyone who truly produces food has a story. This matters because it changes how you see the producer. It reveals their goals, their motivation, their strengths, and their weaknesses. It brings them closer and builds trust. At the same time, it offers a glimpse into what they actually do. I've decided to do the same.

Who we are (because I'm not doing this alone), why we do it, how long we've been doing it, how we do it, and what we do it with. Every time you come here to read, you'll get a story.

And as a physician, I'll share what I know.

If you feel like it, you'll come visit us. If our terms are acceptable to you, and we enjoy working with you as well, we'll provide you with the food we produce. We'll introduce you to other people. We'll show you how we cook (although Rozi does a much better job of that in the "(Y)Eat for Your Life" group), and what we cook with.

If you're interested, you'll stay. If not, you'll move on. I'm old. I have no intention of arguing. If you have a question, ask it. If I know the answer and have the time, I'll respond.

The first story is about how a man named Ferenc Jánosi taught me to quickly grasp the essence of things. If I remember correctly, the technique was called "skimming." The idea was to review a document from a completely unfamiliar field as quickly as possible, without having any expertise in that field. The goal was not to understand every detail but to rapidly identify the main ideas, the structure, and the relationships between concepts.

This is the approach you'll need when reading the kinds of texts I'll be sharing in the future. Don't insist on understanding everything. Read through it. Don't stop. Don't analyze. Don't go back to the previous sentence. When you're finished, put it down.

Whatever your brain managed to absorb is yours. Whatever it can supplement and process using knowledge you've acquired in the past will eventually become useful. I don't know a simpler or more effective method.

The attached text is Part One of Chapter 12. The rest is already written, but if I post it all at once, you'll get lost in it. So that's enough for today. Chapter Two will answer the question that was asked: How does food affect the gut microbiome, the medications we take, and the f***l microbiota transplantation procedures we perform?

The guide is titled *Microbiota Handbook*, and—as many of you suggested—I uploaded it in the first comment while having a conversation with myself.

The millennia-old cornerstone — fructan + quercetin dual matrix in every kitchen.What does it provide? Inulin-type fruct...
05/06/2026

The millennia-old cornerstone — fructan + quercetin dual matrix in every kitchen.

What does it provide? Inulin-type fructans (0.1–2 g/100 g) and quercetin glycosides (especially in the skin) — selective bifidogenic effect and polyphenol-mediated anti-inflammatory action.

How much? ½–1 medium onion (≈ 50–100 g)/day; for IBS-sensitive: onion-infused oil (onion soaked in hot oil, then removed — the flavor is fat-soluble, the FODMAP fructan remains water-soluble, so it doesn't enter the oil).

When to avoid? Large amounts during warfarin or DOAC therapy (anticoagulant interaction), IBS elimination phase, 2 weeks before scheduled surgery in large doses, GERD flare.

The millennia-old cornerstone — fructan + quercetin dual matrix in every kitchen.

Széklet-donorokat keresünk!Ha egészséges vagy, rendszeresen sportolsz és ennek az állapotnak folyamatos orvosi felügyele...
13/04/2026

Széklet-donorokat keresünk!

Ha egészséges vagy, rendszeresen sportolsz és ennek az állapotnak folyamatos orvosi felügyelete mellett az is fontos számodra, hogy másokon segíts, akkor Téged keresünk!

Rendszeres egészségügyi szűréssel, saját mikrobiotád letárolásával és rendszeres, antibiotikum-mentes legeltett állatokból származó termékekkel támogatjuk az egészségedet.

Segíts a kórházi fertőzések megszüntetésében!
Ne súrold, gyűjtsd!

(A donátumok gyűjtése általunk biztosított, könnyen használható, higiénikus szett segítségével történik.)

Várjuk jelentkezésed: MicroBiomeBank.com/hu

03/04/2026

Better health doesn’t start with symptoms.

It starts at the source.

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VetBiota — coming soon.

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