Medical Journal of Indonesia

Medical Journal of Indonesia Medical Journal of Indonesia is a peer-reviewed and open access journal.

Can Physalis angulata prevent bleomycin-induced lung injury?This case-control experimental study evaluated whether oral ...
04/08/2026

Can Physalis angulata prevent bleomycin-induced lung injury?

This case-control experimental study evaluated whether oral P. angulata extract at 50 or 100 mg/kgBW could reduce lung inflammation and fibrosis in bleomycin-exposed rats.

The findings showed no statistically significant reduction in BAL leukocyte count, IL-6, lung injury score, fibrosis score or area, hydroxyproline, TGF-β, or MMP-13. These results are important because they clarify the limits of P. angulata at the tested doses and treatment duration, while supporting the need for further mechanistic and dose-response studies.

The graphical abstract summarizes the study design, measured biomarkers, key results, and conclusion in a concise visual format.

Read the full article for complete methods and interpretation, and share your thoughts in the comments.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Wibowo SAK, Rumende CM, Isbagio H, Setiyono A, Setiabudy R, Rachmadi L, et al. Effects of Physalis angulata extracts on bleomycin-induced rat: analysis on lung inflammation and fibrosis. Med J Indones. 2025;34(4):227–33.

Can a low-cholecalciferol diet support more reliable vitamin D research in mice?This study describes the formulation of ...
16/07/2026

Can a low-cholecalciferol diet support more reliable vitamin D research in mice?

This study describes the formulation of two customized mouse diets with normal and low cholecalciferol content, followed by independent verification of cholecalciferol, calcium, and phosphorus levels. The normal-cholecalciferol diet was also well tolerated during short-term testing, with no adverse events or deaths observed.

These findings matter because clearly defined and verified diets can improve consistency in experimental models investigating vitamin D deficiency.

The graphical abstract summarizes the study design, diet composition, verification process, and key findings in a clear visual format for researchers, healthcare professionals, and students.

Read the full article to explore the complete methods and findings, and share your thoughts in the comments.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Sumariyono, Handayani D, Setiati S, Amalialjinan N, Abellia G, Anindyanti RD, et al. Formulation of mice diet with low cholecalciferol content. Med J Indones. 2025;34(4):221–6.

Can edaravone help protect against hypoxia-related injury?This graphical abstract highlights a case-control experimental...
07/07/2026

Can edaravone help protect against hypoxia-related injury?

This graphical abstract highlights a case-control experimental study evaluating the effects of edaravone on hypoxia-induced lethality and oxidative stress in male Swiss albino mice.

The study assessed three hypoxia models: asphyxia, circulatory, and hemic hypoxia. Edaravone was associated with improved survival across hypoxia models, with stronger protective effects observed in asphyxia and circulatory hypoxia. The findings also suggest reduced hypoxia-induced oxidative stress in brain tissue.

This graphical abstract helps translate the study design, key outcomes, and biological rationale into a clear visual summary for clinicians, researchers, students, and readers interested in oxidative stress and experimental therapeutics.

Read the full article and share your thoughts on the potential role of antioxidant strategies in hypoxia research.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Shaki F, Mokhtaran M, Raei M, Razavi A, Shamshirian A, Eslami S, et al. Effects of edaravone on hypoxia-induced lethality in male Swiss albino mice. Med J Indones. 2025;34(3):146–50.

New issue. New insights. New evidence.Start reading at bit.ly/MJI_Vol35Issue2 🔥 #
01/07/2026

New issue. New insights. New evidence.

Start reading at bit.ly/MJI_Vol35Issue2 🔥

#

Can stem cells support nerve regeneration?This study explores whether adipose-derived mesenchymal stem cells may enhance...
24/06/2026

Can stem cells support nerve regeneration?

This study explores whether adipose-derived mesenchymal stem cells may enhance recovery in a chronic sciatic nerve injury rat model. The findings suggest that AD-MSC treatment was associated with significantly larger nerve fiber diameter, while functional, electrophysiological, and muscle weight outcomes showed favorable but non-significant trends.

Why does this matter? Peripheral nerve injury remains challenging because functional recovery is often limited by poor neuromuscular junction regeneration. Visual summaries can help readers quickly understand the study design, intervention, key outcomes, and clinical relevance before reading the full article.

Read the full article and share your thoughts on the potential role of stem-cell-based approaches in nerve regeneration research.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source:

Can stem cells support nerve regeneration?This study explores whether adipose-derived mesenchymal stem cells may enhance...
24/06/2026

Can stem cells support nerve regeneration?

This study explores whether adipose-derived mesenchymal stem cells may enhance recovery in a chronic sciatic nerve injury rat model. The findings suggest that AD-MSC treatment was associated with significantly larger nerve fiber diameter, while functional, electrophysiological, and muscle weight outcomes showed favorable but non-significant trends.

Why does this matter? Peripheral nerve injury remains challenging because functional recovery is often limited by poor neuromuscular junction regeneration. Visual summaries can help readers quickly understand the study design, intervention, key outcomes, and clinical relevance before reading the full article.

Read the full article and share your thoughts on the potential role of stem-cell-based approaches in nerve regeneration research.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Widodo W, Dilogo IH, Kamal AF, Antarianto RD, Wuyung PE, Siregar NC, et al. Adipose-derived mesenchymal stem cells enhance regeneration in a chronic peripheral sciatic nerve injury Sprague-Dawley rat model. Med J Indones. 2025;34(3):141–5.

Why does quality-of-life measurement matter in thyroid cancer care?This study validates and adapts the Indonesian versio...
16/06/2026

Why does quality-of-life measurement matter in thyroid cancer care?

This study validates and adapts the Indonesian version of the ThyCa-QoL questionnaire (ThyCa-QoL-ID), a disease-specific tool designed to assess quality of life among patients with thyroid cancer.

As thyroid cancer incidence increases in Indonesia, culturally and linguistically appropriate instruments are essential to better understand patient-reported outcomes and support more patient-centered care. The study found that ThyCa-QoL-ID demonstrated acceptable validity, high internal consistency, and cultural adaptation for Indonesian patients.

This graphical abstract summarizes the study design, validation process, key findings, and clinical relevance in a clear visual format—helping readers quickly understand the main message of the article.

Read the full article and share your thoughts on the role of validated quality-of-life tools in cancer care.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Pramono LA, Shatri H, Subekti I, Prihartono NA, Hatma RD, Kurniawidjaja M, et al. Validation and adaptation of the Indonesian version of thyroid cancer quality of life questionnaire. Med J Indones. 2025;34(2):105–9.

Can tumor diffusion metrics help characterize cervical cancer stage?This study evaluates tumor apparent diffusion coeffi...
10/06/2026

Can tumor diffusion metrics help characterize cervical cancer stage?

This study evaluates tumor apparent diffusion coefficient values and apparent diffusion coefficient ratios on diffusion-weighted magnetic resonance imaging in patients with cervical cancer. The findings suggest that tumor apparent diffusion coefficient value may differ between early- and late-stage disease, while apparent diffusion coefficient ratios and histological subtype showed limited discriminatory value.

These results matter because diffusion-weighted magnetic resonance imaging offers non-contrast functional information that may support cervical cancer assessment. The graphical abstract helps summarize the study design, key measurements, and main findings in a clear visual format for clinicians, researchers, students, and readers.

Read the full article and share your thoughts on the potential role of diffusion-weighted magnetic resonance imaging in cervical cancer staging.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Siregar TP, Wanandi SI, Darmiati S, Kusuma F, Sekarutami SM, Lisnawati, et al. Tumor apparent diffusion coefficient value and ratio in magnetic resonance imaging on cervical cancer. Med J Indones. 2025;34(2):99–104.

Frailty in hospitalized older adults is more than a clinical label. It is a signal for vulnerability, complexity, and ri...
02/06/2026

Frailty in hospitalized older adults is more than a clinical label. It is a signal for vulnerability, complexity, and risk.

This study assessed the prevalence and associated factors of frailty among hospitalized geriatric patients at a tertiary hospital in Egypt. Frailty was reported in 59.2% of participants and was associated with factors including older age, female s*x, multimorbidity, cognitive impairment, dementia, falls, incontinence, pressure injury, malnutrition, and polypharmacy.

These findings matter because early recognition of frailty can support more comprehensive geriatric assessment, individualized care planning, and better clinical decision-making.

The graphical abstract summarizes the study design, key findings, and clinical relevance in a concise visual format, helping readers quickly understand the main message of the article.

Read the full article and share your thoughts on frailty assessment in hospitalized older adults.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Elsorady KE, Al Adrosy TI. Prevalence and factors associated with frailty among hospitalized geriatric patients at a tertiary hospital in Egypt. Med J Indones. 2025;34(2):92–8.

Tuberculous uveitis remains an important cause of intraocular inflammation in Indonesia.This paper reports the clinical ...
22/05/2026

Tuberculous uveitis remains an important cause of intraocular inflammation in Indonesia.

This paper reports the clinical profiles and treatment evaluation of patients with tuberculous uveitis at a tertiary eye hospital in Jakarta. The study describes patient characteristics, clinical manifestations, complications, and treatment patterns, including systemic steroids, anti-tuberculosis treatment, and combination therapy.

These findings are relevant for clinicians, researchers, and students because tuberculous uveitis may present with varied ocular manifestations and requires careful diagnostic and therapeutic evaluation. The graphical abstract helps summarize the study design and key findings in a concise visual format for easier reading and discussion.

Read the full article and share your thoughts on the diagnosis and management of tuberculous uveitis in clinical practice.

Disclaimer: This graphical abstract was generated with the assistance of AI for visual communication purposes. The scientific content is derived from the original published article.

Source: Mahayani NMW, Susiyanti M, Sjamsoe S, Utami AN. Clinical profiles and treatment evaluation of tuberculous uveitis in tertiary eye hospital in Jakarta. Med J Indones. 2025;34(2):83–91.

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