05/06/2026
🚨 Latest 3 Update!
🔷 SystImmune and Bristol Myers Squibb presented Phase III data for Izalontamab brengitecan (iza-bren), an investigational EGFRxHER3 bispecific ADC, at ASCO 2026, demonstrating significant survival benefits in both triple-negative breast cancer (TNBC) and esophageal squamous cell carcinoma (ESCC).
🔷 In TNBC, median OS was 15.9 vs 12.5 months and median PFS was 8.5 vs 3.1 months versus chemotherapy. In ESCC, median OS was 9.8 vs 7.2 months and median PFS was 4.2 vs 2.0 months, supporting iza-bren's potential as a new treatment option across multiple difficult-to-treat cancers.
🔗 Read more: https://bit.ly/ONCOnews-04-Jun-05