30/04/2026
🫀 FRANK–STARLING CURVE — The Curve That Decides Fluids 💉
You see hypotension…
Your reflex: “Give fluids!”
But wait 👀
👉 Will fluids actually work? Or just cause edema?
This curve has the answer.
⚡ CORE CONCEPT
👉 “The heart pumps what it receives.”
Within physiological limits:
➡️ ↑ Preload → ↑ Fiber stretch → ↑ Stroke Volume
But ONLY up to a point.
📈 UNDERSTANDING THE CURVE
🟢 Ascending Limb (Fluid Responsive Zone)
✔️ Small ↑ preload → BIG ↑ stroke volume
👉 This is where fluids actually work
🟡 Plateau Phase
✔️ Increasing preload → minimal change in CO
👉 Fluids here = no benefit
🔴 Overstretch Zone (Danger 🚫)
✔️ Excess preload → ↓ contractility
👉 Leads to pulmonary edema + worse outcomes
🧠 CLINICAL TRANSLATION (THIS IS WHAT MATTERS 🔥)
👉 Not all hypotension = fluid deficit
✔️ If on ascending limb → Give fluids
❌ If on plateau → Use vasopressors/inotropes instead
💡 Blind fluid loading = “saline overdose syndrome” 😬
💉 IN OT PRACTICE
✔️ Hypovolemia → curve shifts down → needs volume
✔️ Heart failure / anesthetic depression → curve shifts DOWN
✔️ Inotropes → shift curve UP (better contractility)
👉 Same preload, completely different output = different management
🧠 MEMORY HACK
👉 “Fill the heart… till it works, NOT till it leaks.” 😎
🎯 TAKEAWAY
👉 Fluids are a therapy, not a reflex
👉 Understanding physiology = better decisions in OT
“Not every hypotension needs fluid.
Sometimes, it needs understanding.”
📢 Save • Share • Teach
Because anesthesia = physiology in action 💯
— Anesthesia Made Easy by Dr. Sambit Dash