17/02/2024
I would like to share a simple but very interesting case. 3 yrs old female child resident of Indore, relative of a Paediatrician came to my Rathee hospital with complaint of fever for 11 days, neck stiffness for 3 days from D2 of fever. Child was shown to Paediatrician in Indore where child was given Amoxyclav and zifi in these 11 days. But fever persisted in child.
Child presented to me with complaint of persistence of fever only. Child was playful and physical examination normal. All investigation came normal except raised CRP and TLC but normal neutrophil. Parents complaint of slight behaviour change in child, slight irritable and decrease oral intake.
PROCALCITONIN came negative, CSF examination normal and blood culture shows no growth. USG neck and abdomen normal except matted and necrotic cervical and supraclavicular lymphadenopathy. Now it' s D18 of high grade fever upto 103-104 degree Fahrenheit. Earlier patient was started on piptaz for 2 days and now it' s D6 of meropenem and linezolide. Lymph node FNAC - inconclusive so supraclavicular lymph node excisional biopsy was done- 3 matted lymph node were excised and sent to 3 different lab. BLOCK TEST- gene expert (lal path lab) and histocyto was sent. Except reactive lymph node nothing came positive.
Now fever intensity and frequency decreases and is slightly down to 101 degree Fahrenheit. Repeat PROCALCITONIN again came negative. Till now total 3 blood culture came negative. Weil Felix test came positive so we stop injectables and started doxycycline. But fever intensity increased again to 103. We sent confirmation test for scrub typhus (IgM and IgG Elisa) which came negative.
Now it's nearly 20 days of high grade fever and no physical finding except lymphadenopathy in cervical area. Now b/l submandibular LN appears which were tender. We already did USG neck but to rule out deep seated foci we did CT scan of Neck and thorax.
Atlast we got focus- b/l submandibular collection of pus extending to retropharyngeal, more on left side. We did USG guided aspiration and sent pus culture which grew STAPH.
Dx Retropharyngeal abscess