Pediatric

Pediatric صفحة خاصة بيا للدراسة
مبروكة عمر سالم
MRCPH

*HSP* is typically a self-limited disease and presents with a *classic tetrad:*Palpable purpura *WITHOUT* thrombocytopen...
21/02/2026

*HSP* is typically a self-limited disease and presents with a *classic tetrad:*
Palpable purpura *WITHOUT* thrombocytopenia or coagulopathy – Non-blanching rash, mainly on buttocks and lower limbs
*Arthralgia or arthritis* – Commonly knees and ankles – Non-erosive and transient
*Abdominal pain* – Colicky pain – May cause GI bleeding – Serious complication: intussusception
*Renal* involvement – Microscopic hematuria most common – May progress to nephritic or rarely nephrotic syndrome – Severe cases → rapidly progressive (crescentic) glomerulonephritis*Renal* involvement may appear *late* , even after rash resolves.
Renal involvement typically appears within the first 4–8 weeks, but may develop up to 6 months after onset.
*Recommended monitoring:*
Weekly for 1 month
Every 2 weeks until 3 months
Then at 6 and 12 months
*Check* :
Blood pressure
Urinalysis (hematuria, proteinuria)
Serum creatinine if abnormal findings*Renal disease determines prognosis* in HSP — not the rash.
Development of hypertension, ≥2+ proteinuria, macroscopic hematuria, or nephritic/nephrotic features requires urgent evaluation.
*Even if initial urinalysis is normal,* continue follow-up for at least 6 months (exam favorite).
*Recurrent HSP* episodes are monitored *as a first episode.*

 **5 months  baby with *proteus UTI* *us done and MCUG* , received antibiotics and improved. What is *next* investigatio...
22/01/2026

**5 months baby with *proteus UTI* *us done and MCUG* , received antibiotics and improved. What is *next* investigation?

a) DMSA
b) Mag3.
c) Cystoscopy.
d) Catheter.
e) KUB kidney and ureter.
A

*Simple UTI* :
responds within 48 hr
 *Atypical UTI:*
 seriously ill child
 poor urine flow
 abdominal or bladder mass
 raised creatinine
 septicaemia
 failure to respond to treatment within 48 hr
 infection with organisms other than E. coli

 *Recurrent UTI:*

 ≥2 episodes of UTI with acute pyelonephritis/upper UTI
 1 episode of UTI with acute pyelonephritis/upper UTI plus ≥1 episode or UTI with cystitis/lower UTI
 ≥3 episodes or UTI with cystitis/lower UTI

29/12/2025

12-year-old girl with Type 1 Diabetes Mellitus has poor glycemic control despite increasing insulin dose to 1.5 U/kg/day.

has weight loss, recurrent abdominal pain, and abdominal distension.
*Investigations* :
Hb: 10.8 g/dL (low)
MCV: 66 fL (low)
MCH: normal
HbA1c: 88 mmol/mol (very high)
*Question* :
investigation will most likely lead to the diagnosis?
*Correct Answer* b) Anti-tissue transglutaminase antibodies

with Type 1 DM have a high risk of associated autoimmune diseases, especially celiac disease.

Poor glycemic control despite high insulin doses + weight loss + GI symptoms *strongly suggest* malabsorption.

anemia* with GI symptoms further supports celiac disease.

-tTG antibodies* are the *best initial screening* test.⭕ *Screen* with anti-tTG antibodies ( *even* if *asymptomatic* )

28/12/2025

A 4-year-old girl is newly diagnosed with oligoarticular juvenile idiopathic arthritis (JIA).
The rheumatology consultant refers the child to another department.
The father asks: Which department

ophalamology

⭕Children with *oligoarticular JIA* are at
high risk of *chronic anterior uveitis* , which is often asymptomatic but can cause permanent vision loss if not detected early.

⭕*Regular* ophthalmologic *screening* is mandatory,
*even* in the absence of eye symptoms.

⭕*Oligoarticular* JIA = *automatic ophthalmology referral.*The presence of a positive ANA confers increased risk for asymptomatic anterior uveitis, requiring periodic slit-lamp examination.

The screening recommendations for children with oligoarticular, polyarticular, psoriatic, and undifferentiated JIA are as follows:

●Age at onset 4 and 7 years – Eye examination every 12 months

28/12/2025

Clinical Scenario:

A 2-year-old presents with Fever 39°C), lethargy, vomiting x24h

Received 2x NS boluses (20mL/kg each). Vital Signs:

HR: 185→ 200/min (persistent tachycardia)

RR: 45→ 55/min (tachypnea)

BP: 80/60 78/58 mmHg (mild hypotension)

CRT: 3 sec (unchanged post-fluids)

No hepatomegaly or crackles on exam

Question:

What is the most likely underlying pathophysiology? Options:

a) Intravascular volume depletion

c) Systemic vasodilation.

e) Neurogenic shock

b) Myocardial dysfunction
d) Obstructive shock

-induced myocardial dysfunction

Persistent shock after 40–60 mL/kg fluids in a septic child strongly suggests myocardial dysfunction

so can start inotropesvasodilation means (warm shock) so Warm extremities, brisk CRT.

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