Prolistem Africa SpermHope

Prolistem Africa SpermHope New Ventures
At Prolistem®, we are dedicated to research. Since the birth of our original treatment.

Firstgatemedicals @11
21/02/2026

Firstgatemedicals @11

20/01/2026

Prolistem® Success Story – Nigeria

We are pleased to share a success story reported by our distributor in Nigeria. The patient had a history of zero s***m count confirmed by multiple semen analyses. After completing six months of Prolistem®, a follow-up test revealed 10 million s***m in the semen.

Based on this encouraging improvement, the patient was advised to continue treatment with Prolistem® Plus for an additional three months to further support s***m quality and maturation. Hormonal test results were not available in this case.

We sincerely thank our Nigerian distributor for their dedicated follow-up and for sharing this valuable outcome.

20/01/2026

Prolistem® Success Story – From Zero to Hope

At Farah Fertility Center, under the care of Dr. Faisal Al Omar, a remarkable outcome was achieved for a man diagnosed with non-obstructive azoos***mia (NOA).

Two years earlier, the patient had undergone a testicular biopsy that failed to find s***m, leaving very limited options and little hope.

After starting Prolistem® and completing the full 6-month treatment protocol, a follow-up semen analysis revealed an unexpected and life-changing result:

👉 More than 2,000 s***m were detected directly in the semen.

These s***m were successfully collected and prepared for IVF/ICSI, allowing the couple to move forward without repeating invasive surgical procedures.

Why this case matters
• Demonstrates that even after a failed biopsy, recovery of s***m in NOA is possible
• Highlights the importance of time, consistency, and targeted biological support
• Reinforces Prolistem’s philosophy: work on the root environment of s***matogenesis—not just the outcome

“Every s***m counts. Sometimes, giving the te**is the right conditions—and enough time—can change the story.”

This success adds to the growing real-world evidence that Prolistem® can open a new door for men with NOA, especially before repeating invasive interventions like micro-TESE.

Results may vary. Prolistem is a supportive treatment and does not guarantee success in all cases.

20/01/2026

If no s***m is found in the semen after using Prolistem for 6 months (or even 12 months), the next step is usually micro-TESE.

Recovering s***m production in men with non-obstructive azoos***mia is not always possible, because many known and unknown factors can affect the success rate. Prolistem is designed to support the testicles and improve the chances of finding s***m, but results can vary from one patient to another.

The main goal of Prolistem is to increase the success rate of micro-TESE, and studies showed a significant improvement in outcomes after using Prolistem.
That’s why micro-TESE should always be part of the plan—especially if s***m is not detected in semen after treatment.

Important Note: Success rates vary and are not guaranteed.

20/01/2026

Prolistem® Success: From Sertoli Cell-Only to S***m Retrieval — An Extremely Rare Fertility Case

A male patient was previously treated with chemotherapy for non-Hodgkin lymphoma, resulting in severe and long-term testicular damage. As part of his oncological management, one te**is was surgically removed (orchiectomy), leaving the patient with only one remaining te**is and a critically limited testicular reserve.

Before starting Prolistem®, the patient underwent a micro-TESE procedure, which was negative. Histopathological examination revealed Sertoli Cell-Only syndrome, confirming the absence of active s***matogenesis at that time. His hormonal profile demonstrated extremely elevated FSH levels (>100 IU/L), reflecting profound testicular failure and an exceptionally poor fertility prognosis.

Despite these severe clinical findings, the patient proceeded with Prolistem® treatment.

After completion of the treatment, a repeat micro-TESE was performed. In contrast to the previous outcome, s***m were successfully retrieved, and three vials of s***m were cryopreserved for future IVF/ICSI use.

This case represents an exceptionally rare clinical scenario combining chemotherapy for non-Hodgkin lymphoma, orchiectomy of one te**is, Sertoli Cell-Only histology, extremely high FSH levels, and a previously failed micro-TESE, in which successful s***m retrieval was ultimately achieved following Prolistem® treatment.

Prolistem® does not guarantee results. Its goal is to optimize the testicular environment and maximize the chance of s***m retrieval in the most challenging cases—because every s***m matters.

The diagnosis was made by Dr. Badr Al-Suhaiba, and the microscopic examination was conducted by Dr. Ahmed Al-Khateeb, Amman, Jordan.

Understanding Azoos***mia and FSH LevelsIn men with non-obstructive azoos***mia (NOA), high FSH (follicle-stimulating ho...
11/06/2025

Understanding Azoos***mia and FSH Levels

In men with non-obstructive azoos***mia (NOA), high FSH (follicle-stimulating hormone) levels are often seen—but they are not the cause of the problem.

High FSH is the body’s natural response to testicular failure, trying to stimulate s***m production when the testicles are not functioning properly. This condition is known as primary testicular failure.

It’s important to understand: reducing FSH will not restore s***m production, because FSH is a consequence, not the cause, of azoos***mia.

***mia

28/04/2025

What does high FSH mean in azoos***mia?
It means non-obstructive azoos***mia—specifically, primary testicular failure.
When FSH is high, the testicles aren’t producing s***m properly.
If FSH is normal, more tests are needed to know the cause.
***mia

28/04/2025

Can Prolistem Help in AZF Genetic Disorders?

Azoos***mia caused by AZF deletions (AZFa, AZFb, and AZFc) is one of the most difficult forms of male infertility.

While AZFa is typically linked to a complete absence of s***m, men with AZFb or AZFc deletions may still have isolated areas of s***m production.

Prolistem is designed to activate these remaining active tubules. In some cases of AZFb and AZFc, it may improve the chances of finding s***m—especially when followed by microTESE.

Each case is unique, but even with genetic causes, there is still room for hope.

***mia

Question:How many microTESE procedures can a man with azoos***mia safely undergo during his fertility journey?Answer:The...
28/04/2025

Question:
How many microTESE procedures can a man with azoos***mia safely undergo during his fertility journey?

Answer:
There is no strict limit on the number of microTESE procedures a man can undergo, but most experts recommend no more than 2–3 attempts in a lifetime.

Recent studies and clinical guidelines suggest that each microTESE can cause scarring and reduce testicular function, especially in men with non-obstructive azoos***mia (NOA). The success rate is highest during the first or second procedure, particularly when combined with treatments like Prolistem® that improve the chances of finding s***m.

Before repeating microTESE, it’s important to:
• Evaluate hormone levels (FSH, LH, testosterone)
• Allow enough time for testicular recovery (at least 6–12 months between surgeries)
• Consider treatments that may stimulate remaining s***m production.

Always consult a fertility specialist to plan the best approach based on your unique case.

***mia

FAQ: Does testosterone reduction impact my health?With Prolistem®, testosterone is reduced by only 15–20%—just enough to...
16/04/2025

FAQ: Does testosterone reduction impact my health?
With Prolistem®, testosterone is reduced by only 15–20%—just enough to stimulate the body’s backup s***m production pathway.
This small, natural reduction does not affect overall health, energy, or libido.
It’s a safe and targeted strategy to help men with azoos***mia produce s***m for IVF.

***mia

16/04/2025

Is Prolistem® Approved and Where Is It Made?
Prolistem® is proudly manufactured in the United States in a GMP-certified facility, ensuring high standards of quality and safety. It holds a Certificate of Free Sale from the FDA, confirming it meets U.S. regulatory requirements. In every country where Prolistem® is sold through official distributors, it has been registered and approved by the local Ministry of Health.

22/03/2025

Webinar Recap: Prolistem – A Game Changer for Azoos***mia Treatment in Nigeria

We were honored to host a special webinar for doctors in Nigeria, focusing on Prolistem – a breakthrough treatment for men suffering from non-obstructive azoos***mia.

During the session, doctors shared inspiring success stories from their clinical experience with Prolistem, highlighting its potential to bring hope where there were once limited options.

The webinar also delved into the scientific mechanism behind Prolistem, explaining how it works to stimulate s***matogenesis in difficult cases.

Our goal is to raise awareness among medical professionals and help more patients discover this innovative and promising solution.

Stay tuned for future webinars and collaborations as we continue to expand Prolistem’s reach across Africa.

Interested in learning more? Contact us to join our next event.

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No25 Battalion3 Street Mararaba , First Gate Clinic
Wuse

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+2347030066883

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