30/04/2026
🧬 Struggling with Weight? It Might Be in Your DNA!
Not all weight gain is about diet and exercise. Your genes play a major role in how your body stores fat, controls appetite, and responds to food.
Introducing our Obesity + Metabolic Genetic Panel (40 Genes) — a powerful DNA test designed to uncover the real reason behind weight gain and metabolic issues.
🔍 What this test reveals:
✔️ Genetic tendency for obesity
✔️ Appetite & hunger regulation (Leptin, MC4R pathway)
✔️ Fat storage & metabolism efficiency
✔️ Insulin resistance & diabetes risk
✔️ Energy burning & thermogenesis
✔️ Personalized diet & lifestyle insights
💡 Why this matters?
Stop guessing. Start following a science-based, personalized plan tailored to your body.
👨⚕️ Ideal for:
• Overweight / Obese individuals
• Patients with slow metabolism
• Repeated diet failure cases
• Nutritionists & doctors for personalized care
📊 Sample: Blood
🌍 International Testing Standards
📄 Detailed Clinical Report + Recommendations
Test Name: Obesity & Metabolic Genetic Panel (40 Genes)
Comprehensive Genetic Profiling for Obesity & Metabolic Health
The Obesity & Metabolic Genetic Panel is a comprehensive 40-gene analysis designed to evaluate an individual’s inherited predisposition to obesity, metabolic imbalance, insulin resistance, and related lifestyle response patterns.
This panel provides insight into key biological pathways involved in appetite regulation, energy expenditure, fat metabolism, glucose handling, and neurobehavioral control of eating, enabling a personalized approach to nutrition, fitness, and weight management.
1. Adipokines & Hormonal Regulation
Genes regulating appetite, satiety, and fat signaling pathways:
LEP, LEPR – Leptin signaling (satiety control)
ADIPOQ, RETN – Adiponectin & resistin (insulin sensitivity, fat metabolism)
GHRL – Ghrelin (hunger stimulation)
CCK, PYY – Satiety regulation hormones
NPY, AGRP, POMC, CARTPT – Central appetite control pathways
2. Energy Balance & Obesity Susceptibility
Core genes associated with weight gain and energy homeostasis:
FTO – Strongest known genetic obesity risk marker
MC3R, MC4R – Melanocortin pathway (appetite & energy balance regulation)
TMEM18, NEGR1, SIM1, SDC3 – Hypothalamic control of body weight
3. Insulin Resistance & Glucose Metabolism
Genes influencing blood sugar regulation and diabetes risk:
IRS1, ENPP1, PTP1B – Insulin signaling regulation
GLUT4 (SLC2A4) – Cellular glucose uptake
PPARG – Fat storage & insulin sensitivity
ADRB2, ADRB3 – Lipolysis and metabolic rate modulation
4. Lipid & Fat Metabolism
Genes involved in fat breakdown, storage, and energy utilization:
SREBP1 – Lipid synthesis regulation
ADRB2, ADRB3 – Fat mobilization and thermogenic response
PPARGC1B (PGC1 pathway) – Mitochondrial energy production
UCP1, UCP3 – Thermogenesis and calorie burning in adipose tissue
5. Brain, Reward & Eating Behavior
Genes influencing cravings, reward response, and eating behavior:
BDNF – Appetite regulation & neuroplasticity
NTRK2 – Brain-derived metabolic signaling
DYRK1B – Association with metabolic syndrome and obesity tendency
6. Insulin, Growth & Metabolic Regulation
Key modulators of endocrine and metabolic balance:
NAMPT (PBEF) – Insulin secretion & metabolic regulation
GIPR – Glucose-dependent insulin response pathway
NR0B2 (SHP) – Energy homeostasis regulation
7. Additional Metabolic Modifiers
Genes influencing cardiovascular and metabolic response:
ADD1 – Sodium retention & hypertension risk
ADRB2 / ADRB3 variants – Exercise and diet response variability
UCP1 / UCP3 – Basal metabolic rate & fat oxidation efficiency
Clinical Utility
This panel supports precision lifestyle and medical planning in:
Obesity risk prediction & stratification
Personalized diet and nutrition planning
Exercise response optimization
Metabolic syndrome risk assessment
Supportive insight for weight-loss pharmacogenomics
📞 Book now: 0307-4561958
🌐 Visit: www.dnalabpakistan.com
✨ Know Your Genes. Control Your Weight. Transform Your Life.
ObesityTest
