Clinical Diabetology

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Clinical Diabetology Clinical Diabetology is a bimonthly open access journal focused on diabetes research and education.

📖 Clinical Diabetology — Vol. 15, No. 4 (2026) is now available!Dear Readers,we are pleased to announce the publication ...
04/09/2026

📖 Clinical Diabetology — Vol. 15, No. 4 (2026) is now available!

Dear Readers,
we are pleased to announce the publication of the latest issue of Clinical Diabetology. The new issue brings together research, reviews and scientific correspondence addressing diabetic kidney disease, cardiovascular risk assessment, kidney transplantation, social factors associated with diabetes complications, and diabetic retinopathy.

🔹 Editorial

📌 Can Discordance Between Creatinine- and Cystatin C-Based eGFR Improve Cardiovascular Risk Stratification in Diabetic Kidney Disease?
An editorial perspective on the potential role of discordance between creatinine- and cystatin C-based estimates of kidney function in cardiovascular risk assessment in diabetic kidney disease.

🔹 Research papers

📌 eGFR Difference for All-Cause and Cardiovascular Mortality in Diabetic Kidney Disease — a NHANES Analysis
An analysis exploring whether differences between estimates of glomerular filtration rate may provide additional prognostic information in patients with diabetic kidney disease.

📌 Sodium-Glucose Cotransporter Type 2 Inhibitors As a Promising Tool for Diabetologists and Nephrologists in Post-Transplant Care — Observational Study
An observational study examining the use of SGLT2 inhibitors in kidney transplant recipients, with particular attention to graft function, metabolic parameters and safety observations.

📌 Low Educational Attainment Is Associated with Increased Risk of Complications in Type 2 Diabetes — a Multivariable Analysis
A study investigating the relationship between educational attainment and the burden of diabetes-related microvascular and macrovascular complications.

🔹 Review article

📌 Statins and Fenofibrate in Diabetic Retinopathy — a Narrative Review of Recent Clinical Evidence
A narrative review of recent clinical evidence concerning the potential role of statins and fenofibrate in the onset and progression of diabetic retinopathy.

🔹 Observation letters

📌 Elevated Serum Endocan Concentrations in People with Type 2 Diabetes and Diabetic Retinopathy
An investigation of serum endocan as a marker related to endothelial dysfunction in people with type 2 diabetes and diabetic retinopathy.

📌 Relationship Between FIB-4 Index and Salt Intake
A study examining the relationship between estimated salt intake and the FIB-4 index in people with type 2 diabetes.

🔹 Letters to the Editor

📌 SGLT2 Inhibitors in Kidney Transplant Recipients: Promising Signals, But Limited Evidence
A methodological discussion highlighting the need for caution when interpreting currently available evidence on SGLT2 inhibitors in kidney transplant recipients.

📌 Authors’ response to: SGLT2 Inhibitors in Kidney Transplant Recipients: Promising Signals, But Limited Evidence
The authors respond to the methodological concerns and clarify the exploratory, hypothesis-generating nature of their observations.

🔗 Clinical Diabetology online:
https://journals.viamedica.pl/clinical_diabetology/issue/view/6897

A recent review summarizes the current evidence on type 2 diabetes remission and relapse after metabolic and bariatric s...
24/08/2026

A recent review summarizes the current evidence on type 2 diabetes remission and relapse after metabolic and bariatric surgery, including the underlying mechanisms, predictive factors, and postoperative management.

Reported T2D remission rates after bariatric surgery exceed 70% in some studies, although relapse remains relatively common. Shorter diabetes duration, lower preoperative HbA1c, preserved β-cell function, absence of insulin therapy, and younger age are associated with a greater likelihood of remission. Evidence also suggests that Roux-en-Y gastric bypass may provide more durable glycemic control and lower relapse rates than sleeve gastrectomy.

Authors: Julia Ciesielska, Kacper Bartosik, Michał Niewęgłowski, Stanisław Marczuk, Iga Nazaruk, Justyna Wyroślak-Najs

📄 Read the full article:
https://journals.viamedica.pl/clinical_diabetology/article/view/112355

A Proteomic Study Reveals the Relationship Between Arterial Stiffness and Hyperglycemia in Middle-Aged Obese MenA recent...
28/07/2026

A Proteomic Study Reveals the Relationship Between Arterial Stiffness and Hyperglycemia in Middle-Aged Obese Men

A recent cross-sectional proteomic study of 82 middle-aged men with obesity explored the molecular relationship between arterial stiffness and hyperglycemia. Among the components of metabolic syndrome, hyperglycemia was the only one that differed significantly across the cardio-ankle vascular index categories.

Proteomic analyses identified the “fluid shear stress and atherosclerosis” pathway as significantly enriched in both arterial stiffness and hyperglycemia. The researchers identified 18 shared proteins involved in antioxidant defense, vascular inflammation, mechanosensing, and intracellular signaling.

These results are preliminary and require confirmation in larger studies, as only four participants met the criteria for arterial stiffness. Moreover, the association between fasting plasma glucose and arterial stiffness was no longer statistically significant after adjustment for age and systolic blood pressure.

Authors: Thanutchaporn Nutmakul, Nontawit Auppawat, Sittiruk Roytrakul, Jintana Sirivarasai, Sirasa Ruangritchankul, Wutarak Monsuwan

DOI: https://doi.org/10.5603/cd.112259

📖 Clinical Diabetology - Vol. 15, No. 3 (2026) is now available!Dear Readers,We are pleased to inform you that the lates...
01/07/2026

📖 Clinical Diabetology - Vol. 15, No. 3 (2026) is now available!

Dear Readers,
We are pleased to inform you that the latest issue of Clinical Diabetology has been published online.

This issue presents editorials, research papers, a review article and an observation letter covering clinically relevant topics in diabetology - from glycemic targets, microvascular complications and diabetic retinopathy to cognitive function, insulin resistance, lifestyle factors, body composition and telehealth-based diabetes care.

🔍 In this issue:

🔹 Editorial
📌 Time-in-Range versus Time-in-Tight-Range Goals for Managing Diabetes
A clinically oriented discussion on individualized glycemic targets and the role of CGM-derived metrics in diabetes management.

🔹 Research papers
📌 Effect of Tight Glycemic Control on Microvascular Complications in Type 2 Diabetes Mellitus — a Randomized Controlled Trial in an Egyptian Cohort
A randomized study addressing glycemic targets and short-term microvascular outcomes in patients with type 2 diabetes.

📌 Glycemic Control and Serum Irisin Levels in Relation to Cognitive Function in Type 2 Diabetes — Cross-Sectional Study
An analysis of the relationship between metabolic control, serum irisin levels and cognitive performance in type 2 diabetes.

📌 Clinical Evaluation of the Effectiveness of Berberine on Insulin Resistance in Patients with Type 2 Diabetes Mellitus
A clinical evaluation of berberine as an adjunctive intervention in patients with type 2 diabetes and insulin resistance.

📌 LIMU — Lifestyle Investigation at the Medical University: The Relationship Between Lifestyle and Dietary Habits and Body Composition Among Students of the Medical University of Lublin — Cross-sectional Study
A study exploring lifestyle, dietary habits and body composition among medical students.

🔹 Review article
📌 Telehealth for Glycemic Control Among People with Diabetes in Brazil — an Integrative Review
A review of telehealth-based approaches supporting glycemic control and diabetes care in Brazil.

🔹 Observation letter
📌 Analysis of the Ratio of Intercellular Adhesion Molecule-1 and High-Density Lipoprotein Serum of Subjects with Diabetic Retinopathy
An observation letter focused on inflammatory and lipid-related markers in diabetic retinopathy.

Higher fasting plasma glucose levels, even within the normal range, may be associated with a greater long-term decline i...
29/06/2026

Higher fasting plasma glucose levels, even within the normal range, may be associated with a greater long-term decline in percent vital capacity in individuals with persistent normal glucose tolerance.

In this observation letter, the authors followed individuals with sustained normal glucose tolerance for 11 years and found that higher baseline fasting plasma glucose was independently associated with a greater decline in %VC.

Authors: Shuichi Okada, Koji Kashima, Hiroki Dobashi, Daiki Shioya, Junichi Okada, Kazuya Okada, Eijiro Yamada, Tsugumichi Saito, Kihachi Ohshima, Koji Kikkawa

Can lipid-lowering therapy offer benefits beyond cardiovascular protection in patients with diabetic retinopathy?This na...
08/06/2026

Can lipid-lowering therapy offer benefits beyond cardiovascular protection in patients with diabetic retinopathy?

This narrative review summarizes recent clinical evidence from 2020–2025 on statins and fenofibrate in diabetic retinopathy. While glycemic and blood pressure control remain essential, the reviewed data suggest that fenofibrate may be associated with more favorable retinal microvascular outcomes, including reduced progression and lower treatment burden in patients with established retinopathy. Evidence for statins, however, remains heterogeneous and clinically intriguing.

Authors: Weronika Dmoch, Julia Sawicka, Natalia Żelichowska, Zuzanna Kępczyńska, Piotr Maciejewicz, Dariusz Kęcik

💙 Clinical Diabetology — New issue Vol. 15, No. 2 (2026) has been publishedDear Readers,We are pleased to inform you tha...
04/05/2026

💙 Clinical Diabetology — New issue Vol. 15, No. 2 (2026) has been published

Dear Readers,
We are pleased to inform you that the current issue of Clinical Diabetology is now available online. We hope you will find it of interest.

This issue focuses on practical and clinically relevant topics in diabetology, including automated insulin delivery systems, nutritional awareness, diabetic peripheral neuropathy, pharmacotherapy in type 2 diabetes, inflammatory and renal markers, and diabetes technology in young children.

🔹 Editorial
📌 Automated Insulin Delivery for All Insulin-Treated Diabetes: The Evidence Is Ready, Is Policy?
A timely commentary on the expanding evidence for automated insulin delivery and the need to address access, reimbursement, and implementation in clinical practice.

🔹 Research papers
📌 Awareness of Caloric Requirement Is Limited Among Polish Population — Survey Study
A survey-based analysis highlighting gaps in public awareness of daily caloric requirements and their relevance for obesity prevention and lifestyle counseling.

📌 Effect of Neural Mobilization on Pain, Conduction Velocity and Muscle Activity in Diabetic Peripheral Neuropathy — Multi-arm Randomized Controlled Study
A randomized study assessing neural mobilization as an adjunctive physiotherapeutic approach in patients with diabetic peripheral neuropathy.

🔹 Review articles
📌 Comparative Efficacy and Safety of Ipragliflozin vs. Sitagliptin for Type 2 Diabetes — a Systematic Review and Meta-Analysis
A systematic review and meta-analysis comparing two pharmacological options for type 2 diabetes with regard to glycemic, metabolic, and safety outcomes.

📌 An Overview of Automated Insulin Delivery (AID) Systems in Poland in 2025 — Principles, Available Technologies and Future Perspectives
A practical overview of AID systems available in Poland, including their principles, clinical applicability, limitations, and future directions.

🔹 Letters
📌 Use of Diluted Rapid-Acting Insulin in the Minimed™ 780G Automated Insulin Delivery System in a Young Child with Type 1 Diabetes
A case-based report on the use of diluted insulin in a young child with very low insulin requirements using an automated insulin delivery system.

📌 Adiposity Indicators as Determinants of High-Sensitivity C-Reactive Protein in Type 2 Diabetes — a Cross-Sectional Study
An observational letter exploring the relationship between adiposity measures and low-grade systemic inflammation in type 2 diabetes.

📌 Thyroid Stimulating Hormone is Positively Associated with the Urinary Albumin-to-Creatinine Ratio in People with Type 2 Diabetes
An observational analysis addressing the relationship between thyroid function markers and albuminuria in people with type 2 diabetes.

A standard creatinine-based eGFR may not tell the whole story in diabetic kidney disease. This NHANES analysis explores ...
08/04/2026

A standard creatinine-based eGFR may not tell the whole story in diabetic kidney disease. This NHANES analysis explores whether the gap between cystatin C– and creatinine-based eGFR (eGFRdiff) adds prognostic value in DKD, suggesting that patients with eGFRdiff < –10 mL/min/1.73 m² may carry substantially higher all-cause and cardiovascular risk. A thought-provoking read for clinicians interested in cardio-renal risk stratification and earlier identification of high-risk patients.

Authors: Jialin Lu, Yixin Wang, Xiangchun Xu, Xuyu He

📢 Clinical Diabetology — New issue: Vol. 15, No. 1 (2026) is now online!This issue covers practical questions in diabeti...
05/03/2026

📢 Clinical Diabetology — New issue: Vol. 15, No. 1 (2026) is now online!

This issue covers practical questions in diabetic kidney disease, individualized therapy in older adults, DKA hospitalization factors, AI wearables in diabetes care, and glycemic variability around delivery in T1D pregnancy.

🔹 EDITORIALS

✅ Is Diabetic Kidney Disease Always Purely Related to Diabetes?
A clinical perspective on when renal disease in people with diabetes may have non-diabetic causes and what should raise diagnostic suspicion.

✅ When More Is Less: Rethinking Early Combination Therapy in Older Adults with Type 2 Diabetes
A commentary on balancing early glycemic control with treatment burden, safety, and individual goals in older adults with T2D.

🔹 RESEARCH PAPERS

📌 Effect of Systemic Immune-Inflammation Index and Inflammatory Markers on Length of Hospital Stay in Diabetic Ketoacidosis: a Retrospective Study
Explores whether readily available inflammatory indices may help anticipate hospital length of stay in DKA.

📌 Achievement of Glycated Hemoglobin Targets and Associated Factors in Older Adults with Type 2 Diabetes in Vietnam: a Cross-Sectional Study
Real-world evaluation of HbA1c target attainment in older adults and factors linked with better or worse control.

📌 Assessing User Intentions Towards Artificial Intelligence-Powered Wearable Diabetes Devices — Single Center, Cross-Sectional Study
Looks at what drives patients’ willingness to use AI-enabled wearable diabetes devices, with implications for implementation.

📌 The Relationship Between HbA1c Concentration and Glycemic Variability Parameters Assessed Peripartum in Women with Type 1 Diabetes: Retrospective Study
Assesses how HbA1c relates to CGM-based glycemic variability around delivery in women with T1D.

🔹 LETTERS

🩺 IgA Vasculitis in a Patient with Type 2 Diabetes Complicated by Severe Diabetic Nephropathy
A case highlighting diagnostic complexity when systemic vasculitis occurs in a patient with advanced diabetic kidney disease.

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