Dental and Medical Problems

Dental and Medical Problems Dane kontaktowe, mapa i wskazówki, formularz kontaktowy, godziny otwarcia, usługi, oceny, zdjęcia, filmy i ogłoszenia od Dental and Medical Problems, Zdrowie i medycyna, Ulica K. Marcinkowskiego 2-6, Wroclaw.

Dental and Medical Problems is an international, peer-reviewed, open access journal covering aspects of oral sciences and general medicine, published bimonthly by Wroclaw Medical University.

🦷 From the Oral Cavity to the Immune System: How Periodontal Health Reflects Overall HealthOral health may reveal much m...
11/08/2026

🦷 From the Oral Cavity to the Immune System: How Periodontal Health Reflects Overall Health

Oral health may reveal much more about our immune system than we realize.

A new study published in Dental and Medical Problems, based on data from more than 465,000 UK Biobank participants, found that individuals reporting symptoms of periodontal problems were more likely to develop selected autoimmune diseases, including psoriasis, lichen planus and primary biliary cholangitis.

Although the study does not establish a causal relationship between periodontal disease and autoimmune disorders, its findings add to the growing body of evidence suggesting that periodontal and systemic immune health are closely interconnected.

📖 Read the full article: https://dmp.umw.edu.pl/en/article/2026/63/3/567/

🔊 Listen to the podcast: https://on.soundcloud.com/q2vX15b7J95JhPIZYL

🧪 Molecular signature of periodontitis progression in salivaClinical and radiographic assessments remain central to peri...
04/08/2026

🧪 Molecular signature of periodontitis progression in saliva

Clinical and radiographic assessments remain central to periodontitis grading, but they provide limited direct information about the molecular processes associated with different progression rates. In this case–control study, salivary SOST, DKK1 and WNT5a differentiated periodontal health from periodontitis with AUC values of 0.96–0.99. WNT5a was highest in Grade C and SOST and DKK1 were highest in Grade B disease. These distinct biomarker profiles may support the future development of saliva-based tools that complement conventional grading, improve risk assessment and guide personalized monitoring.

Specific implications and potential applications:

🔸WNT5a as a candidate marker of rapid disease progression

🔸SOST and DKK1 as potential indicators of altered WNT-mediated bone remodeling

🔸Strong associations between biomarker concentrations and clinical periodontal parameters

🔸A basis for developing combined biomarker panels for diagnosis and follow-up

🔸Need for external validation in larger, longitudinal and more diverse populations

🔗 Read more: https://dmp.umw.edu.pl/en/article/2026/63/2/335/

🦷 Exploring a Propolis-Based Approach to Alveolar Ridge PreservationPreserving alveolar bone after tooth extraction rema...
28/07/2026

🦷 Exploring a Propolis-Based Approach to Alveolar Ridge Preservation

Preserving alveolar bone after tooth extraction remains clinically important because post-extraction resorption may complicate subsequent prosthetic and implant rehabilitation. In this in vivo study, the combination of a natural propolis extract with a bovine xenograft was associated with greater type I collagen expression and lower NF-κB, TLR2 and TNF-α expression during socket healing. The findings indicate that propolis-containing biomaterials merit further investigation as modulators of inflammation and bone regeneration, while their clinical effectiveness still requires confirmation in human studies.

The study suggests several potential implications:

▫️Support for collagen-rich bone matrix formation within the healing socket

▫️Attenuation of inflammatory signaling associated with osteoclastic activity

▫️Possible biological enhancement of xenograft-based ridge preservation materials

▫️Potential application of propolis-derived bioactive compounds in regenerative dentistry

▫️A need for longer observation periods and direct assessment of bone volume and quality

▫️A need to determine whether the composite offers a meaningful advantage over propolis alone

🔗 Read more: https://dmp.umw.edu.pl/en/article/2026/63/2/365/

🧬 Could a periodontal pathogen influence molecular pathways involved in head and neck cancer?The contribution of periodo...
21/07/2026

🧬 Could a periodontal pathogen influence molecular pathways involved in head and neck cancer?

The contribution of periodontal pathogens to head and neck squamous cell carcinoma (HNSCC) remains insufficiently understood, particularly regarding their effects on epithelial gene expression and patient prognosis. This bioinformatics study identified DDIT4 and RCE1 as genes upregulated both in human gingival keratinocytes exposed to Aggregatibacter actinomycetemcomitans and in HNSCC tissues, with higher expression associated with reduced overall survival. These findings may help prioritize molecular targets for experimental validation and support further investigation of host–microbiome interactions in head and neck carcinogenesis.

Specific implications and potential applications include:

▫️Prioritization of DDIT4 and RCE1 as candidate prognostic biomarkers and therapeutic targets

▫️Further investigation of Wnt, Notch, TGF-β, Toll receptor and cadherin-related pathways

▫️Development of experimental models examining how periodontal pathogens alter epithelial cell biology

▫️Integration of periodontal, microbiological and oncological data in HNSCC risk research

▫️Reinforcement of the need for prospective clinical and laboratory validation before causal conclusions can be drawn

🔗 Read more: https://dmp.umw.edu.pl/en/article/2026/63/2/419/

🦷 Rheumatoid arthritis and periodontitis: A clinically relevant connectionRheumatoid arthritis and periodontitis are chr...
14/07/2026

🦷 Rheumatoid arthritis and periodontitis: A clinically relevant connection

Rheumatoid arthritis and periodontitis are chronic inflammatory diseases that may share biological pathways, yet the strength and clinical relevance of their association remain insufficiently defined. This systematic review and meta-analysis found that patients with rheumatoid arthritis had substantially higher odds of periodontitis, with a pooled OR of 11.37. Clinical attachment loss emerged as the most consistently affected periodontal parameter. These findings support closer integration of dental and rheumatologic care, while also highlighting the need for longitudinal studies using standardized diagnostic criteria and more rigorous control of confounding factors.

Specific implications and practical applications include:

▫️Routine periodontal screening in patients with rheumatoid arthritis

▫️Greater attention to clinical attachment loss and moderate-to-severe periodontitis

▫️Closer collaboration between periodontists, dentists and rheumatologists

▫️Assessment of shared risk factors, including smoking, age, obesity and vitamin D deficiency

▫️Further prospective research to clarify causality and the impact of periodontal treatment on rheumatoid arthritis outcomes

🔗 Read more: https://dmp.umw.edu.pl/en/article/2026/63/2/483/

One journal. Two disciplines. Shared excellence. 📘🦷🩺Contemporary biomedical research increasingly addresses problems tha...
07/07/2026

One journal. Two disciplines. Shared excellence. 📘🦷🩺

Contemporary biomedical research increasingly addresses problems that cannot be fully understood within the limits of a single discipline. Dental and Medical Problems responds to this need by serving as an international journal positioned at the intersection of dental science, medicine, biomedical sciences, and public health. This interdisciplinary profile strengthens the journal’s role as a platform for research that connects clinical relevance, scientific quality and international visibility.

The motto “One journal. Two disciplines. Shared excellence.” was created specifically for Dental and Medical Problems to reflect this identity and to express the journal’s continuing development as a coherent, recognizable, and internationally oriented scientific brand.

🔸"One journal" reflects a coherent publishing brand, consistent editorial standards and a stable scientific position.

🔸"Two disciplines" highlights the journal’s profile, connecting dentistry and medicine while remaining open to research that crosses traditional disciplinary boundaries.

🔸"Shared excellence" refers to the quality of the work contributed by authors, reviewers and editors, as well as to the journal’s growing international visibility, indexing, citation impact, and bibliometric performance.

Visit the journal's website: https://dmp.umw.edu.pl/en/home

🪻 Lavender Aromatherapy as a Supportive Strategy for Dental AnxietyDental anxiety remains a clinically relevant barrier ...
30/06/2026

🪻 Lavender Aromatherapy as a Supportive Strategy for Dental Anxiety

Dental anxiety remains a clinically relevant barrier to oral healthcare, particularly in surgical procedures such as mandibular third molar removal, where stress may affect both patient experience and treatment management. In this triple-blind randomized clinical trial, aromatherapy with lavender essential oil was associated with lower post-intervention heart rate, respiratory rate, salivary cortisol levels, and local anesthetic requirement compared with placebo. These findings suggest that lavender aromatherapy may serve as a simple, non-invasive adjunct for modulating acute stress responses in dental settings, although larger trials are needed to confirm its clinical value.

Specific implications and practical applications:

🔸Lavender aromatherapy may be considered as a complementary, non-pharmacological approach for patients with dental anxiety.

🔸The observed reduction in salivary cortisol supports a possible effect on physiological stress response, not only subjective anxiety.

🔸Lower heart and respiratory rates after the intervention may indicate reduced autonomic arousal before oral surgery.

🔸The reduced need for local anesthetic may have practical relevance for patient management, but this finding requires confirmation in larger studies.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2026/63/1/35/

🔍 Nanoparticle Bone Grafts: A New Direction in Bone Regeneration ResearchBone defects in dentistry and medicine remain a...
23/06/2026

🔍 Nanoparticle Bone Grafts: A New Direction in Bone Regeneration Research

Bone defects in dentistry and medicine remain a significant clinical challenge, and current grafting approaches still require materials that combine biocompatibility, osteoconductivity, controlled degradation, and biological activity. This study characterized novel demineralized freeze-dried bovine bone xenograft nanoparticles (DFDBBX-NPs), showing favorable physicochemical properties, high water absorption, slow enzymatic degradation, and higher BMP-2 than collagen-1 content. The findings support further investigation of DFDBBX-NPs as candidate scaffolds for bone tissue engineering and regenerative procedures, while clinical validation remains necessary before routine use.

Specific implications and practical applications:

🔸DFDBBX-NPs may contribute to the development of next-generation bone graft substitutes.

🔸The presence of BMP-2 and collagen-1 supports their potential relevance for osteoinductive and osteoconductive processes.

🔸High water absorption may facilitate biological fluid interaction, nutrient transport and cell infiltration within scaffold structures.

🔸Slow enzymatic degradation suggests potential usefulness where scaffold stability is required during early tissue repair.

🔸Further in vitro, in vivo, and clinical studies are needed to assess safety, immunological response, bone integration, and regenerative efficacy.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2026/63/1/209/

📈 2025 Impact Factor for Dental and Medical ProblemsWe are pleased to announce that the 2025 Impact Factor for Dental an...
18/06/2026

📈 2025 Impact Factor for Dental and Medical Problems

We are pleased to announce that the 2025 Impact Factor for Dental and Medical Problems, released in the 2026 Journal Citation Reports™ (Clarivate™), has increased from 3.9 to 4.3.

The journal is currently ranked as:

🔹 #21/165 in "Dentistry, Oral Surgery & Medicine" (Q1)

🔹 #52/336 in "Medicine, General & Internal" (Q1)

Additional indicators confirm the journal’s continued growth:

✔️ JCI 2025: 1.38

✔️ Immediacy Index increased from 0.7 to 1.2

This achievement reflects the increasing visibility, influence and international recognition of the research published in Dental and Medical Problems. The journal remains the highest-ranked Polish medical journal published by a university in both categories and the third-ranked Polish medical journal overall.

We would like to thank our Authors, Reviewers, Section Editors, Editorial Board Members, and the team of Wroclaw Medical University Press for their expertise and dedication that have contributed to the journal’s success.

Adres

Ulica K. Marcinkowskiego 2-6
Wroclaw
50-368

Godziny Otwarcia

Poniedziałek 08:00 - 16:00
Wtorek 08:00 - 16:00
Środa 08:00 - 16:00
Czwartek 08:00 - 16:00
Piątek 08:00 - 16:00

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