08/11/2026
FAMILIAR STORY
The connections between various metabolic systems
and organ systems is a frequent theme in my articles.
This time the connection is between two very disparate
organ systems, namely, the respiratory system and the
endocrine system. I think you all know by now what the
respiratory system is (nose, trachea, bronchial tubes, air
sacs and lung tissue with its blood supply). The endocrine
system are those organs which produce chemicals that
help to regulate our bodies various functions (thyroid
gland, pituitary gland, pancreas for insulin production,
adrenal glands, etc.)
The connection in this article is between a pulmonary
problem called bronchiectasis which I have written about
recently and also have devoted one of my radio shows
(The Buzz with Dr. Z) to on WRTA. This an anatomic
distortion of the airways caused by repeated inflammation
and infection. The endocrine problem is one of he most
common we see in medicine, specifically, diabetes.
An analysis of over 30,000 patients across four
international registries has found that patients with
bronchiectasis and diabetes have more severe disease
characteristic for their bronchiectasis. What does this
mean and why?
Patients with diabetes have more associated changes
in the body’s markers for inflammation and significant
differences in the type of bacteria cultured from their
airways. This means that patients who have both of these
problems are more at risk for serious lung infections and
as we all know infections can play havoc with blood sugar
management in diabetes.
It is important for your doctor to recognize this
association.